1,4-Naphthoquinone Motif in the Synthesis of New Thiopyrano[2,3-<i>d</i>]thiazoles as Potential Biologically Active Compounds

1,4-Naphthoquinone Motif in the Synthesis of New Thiopyrano[2,3-<i>d</i>]thiazoles as Potential Biologically Active Compounds

A series of 11-substituted 3,5,10,11-tetrahydro-2<i>H</i>-benzo[6,7]thiochromeno[2,3-<i>d</i>][1,3]thiazole-2,5,10-triones were obtained via <i>hetero</i>-Diels-Alder reaction of 5-alkyl/arylallylidene/-4-thioxo-2-thiazolidinones and 1,4-naphthoquinones. The struc...

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Bibliographic Details
Main Authors: Andrii Lozynskyi, Julia Senkiv, Iryna Ivasechko, Nataliya Finiuk, Olga Klyuchivska, Nataliya Kashchak, Danylo Lesyk, Andriy Karkhut, Svyatoslav Polovkovych, Oksana Levytska, Olexandr Karpenko, Assyl Boshkayeva, Galiya Sayakova, Andrzej Gzella, Rostyslav Stoika, Roman Lesyk
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
1,4-naphthoquinones
<i>hetero</i>-Diels-Alder reaction
thiopyrano[2,3-<i>d</i>]thiazoles
X-ray
anticancer activity
cytotoxicity
Online Access:https://www.mdpi.com/1420-3049/27/21/7575

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