Cryo-EM elucidates the uroplakin complex structure within liquid-crystalline lipids in the porcine urothelial membrane

Abstract The urothelium, a distinct epithelial tissue lining the urinary tract, serves as an essential component in preserving urinary tract integrity and thwarting infections. The asymmetric unit membrane (AUM), primarily composed of the uroplakin complex, constitutes a critical permeability barrie...

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Main Authors: Haruaki Yanagisawa, Yoshihiro Kita, Toshiyuki Oda, Masahide Kikkawa
格式: 文件
语言:English
出版: Nature Portfolio 2023-10-01
丛编:Communications Biology
在线阅读:https://doi.org/10.1038/s42003-023-05393-x