Dendritic Cells Expressing MyD88 Molecule Are Necessary and Sufficient for CpG-Mediated Inhibition of IgE Production In Vivo
Elevated levels of immunoglobulin E (IgE) are associated with allergies and other immunological disorders. Sensitization with alum adjuvant favours IgE production while CpG-ODN adjuvant, a synthetic toll-like receptor 9 (TLR9) agonist, inhibits it. The cellular mechanisms underlying in vivo TLR regu...
Main Authors: | Ricardo W. Alberca Custodio, Luciana Mirotti, Eliane Gomes, Fernanda P.B. Nunes, Raquel S. Vieira, Luís Graça, Rafael R. Almeida, Niels O. S. Câmara, Momtchilo Russo |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-09-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/8/10/1165 |
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