Expression of the cobalamin transporters cubam and MRP1 in the canine ileum-Upregulation in chronic inflammatory enteropathy.

Chronic inflammatory enteropathy (CIE) in dogs, a spontaneous model of human inflammatory bowel disease (IBD), is associated with a high rate of cobalamin deficiency. The etiology of hypocobalaminemia in human IBD and canine CIE remains unknown, and compromised intestinal uptake of cobalamin resulti...

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Bibliographic Details
Main Authors: Stefanie Kather, Johannes Kacza, Helga Pfannkuche, Denny Böttcher, Chi-Hsuan Sung, Joerg M Steiner, Gotthold Gäbel, Franziska Dengler, Romy M Heilmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0296024&type=printable