PET-CT in early detection of Alzheimer’s disease: а case report

The article describes a clinical case of a female Alzheimer disease patient at an early stage of the neurodegenerative process. The patient did not have any complaints. She was taken to the neuropsychologists by her husband that was concerned because of the patient's family history (his mother-...

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Main Authors: Semen V. Prokopenko, Boris V. Barankin, Natal'ya М. Mar'ina, Еlena Y. Mozheyko, Аnna F. Bezdenezhnykh, Tat'yana D. Koryagina, Natal'ya G. Chanchikova, Nikolay А. Tokarev, Еlena А. Karlova, Аnastasiya V. Ozerskaya, Еvgeniy А. Badrin, Кirill V. Belugin, Аnastasiya А. Savel'eva, Nikolay V. Shepelevich
Format: Article
Language:English
Published: Research Center of Neurology 2017-12-01
Series:Анналы клинической и экспериментальной неврологии
Subjects:
Online Access:https://annaly-nevrologii.com/journal/pathID/article/viewFile/501/392
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author Semen V. Prokopenko
Boris V. Barankin
Natal'ya М. Mar'ina
Еlena Y. Mozheyko
Аnna F. Bezdenezhnykh
Tat'yana D. Koryagina
Natal'ya G. Chanchikova
Nikolay А. Tokarev
Еlena А. Karlova
Аnastasiya V. Ozerskaya
Еvgeniy А. Badrin
Кirill V. Belugin
Аnastasiya А. Savel'eva
Nikolay V. Shepelevich
author_facet Semen V. Prokopenko
Boris V. Barankin
Natal'ya М. Mar'ina
Еlena Y. Mozheyko
Аnna F. Bezdenezhnykh
Tat'yana D. Koryagina
Natal'ya G. Chanchikova
Nikolay А. Tokarev
Еlena А. Karlova
Аnastasiya V. Ozerskaya
Еvgeniy А. Badrin
Кirill V. Belugin
Аnastasiya А. Savel'eva
Nikolay V. Shepelevich
author_sort Semen V. Prokopenko
collection DOAJ
description The article describes a clinical case of a female Alzheimer disease patient at an early stage of the neurodegenerative process. The patient did not have any complaints. She was taken to the neuropsychologists by her husband that was concerned because of the patient's family history (his mother-in-law suffered of Alzheimer's disease) and the emergence of some memory problems in his wife. The diagnosis was suspected based on the results of neuropsychological evaluation of cognitive functions which corresponded to mild cognitive impairment. To confirm the presence of a neurodegenerative disease brain positron-emission tomography with F-18 fluorodesoxyglucose (FDG) was performed. Hypometabolism of the imaging agent was detected in the temporal and parietal lobes cortex, in the association cortex of the left temporal and the right occipital lobes, and in the posterior part of the left cyngulate gyrus. This findings correlated with the data of the patients cognitive evaluation and thus provided the nosological diagnosis at an early stage of the disease.
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spelling doaj.art-e7f6d74cace943afad7910dd680b4d522022-12-22T00:27:07ZengResearch Center of NeurologyАнналы клинической и экспериментальной неврологии2075-54732409-25332017-12-01114657010.18454/ACEN.2017.4.7382PET-CT in early detection of Alzheimer’s disease: а case reportSemen V. Prokopenko0Boris V. Barankin1Natal'ya М. Mar'ina2Еlena Y. Mozheyko3Аnna F. Bezdenezhnykh4Tat'yana D. Koryagina5Natal'ya G. Chanchikova6Nikolay А. Tokarev7Еlena А. Karlova8Аnastasiya V. Ozerskaya9Еvgeniy А. Badrin10Кirill V. Belugin11Аnastasiya А. Savel'eva12Nikolay V. Shepelevich13Krasnoyarsk State Medical University named after Prof. V.F. Voyno-YasenetskyFederal Siberian Research Clinical CenterFederal Siberian Research Clinical CenterKrasnoyarsk State Medical University named after Prof. V.F. Voyno-YasenetskyKrasnoyarsk State Medical University named after Prof. V.F. Voyno-YasenetskyKrasnoyarsk State Medical University named after Prof. V.F. Voyno-YasenetskyFederal Siberian Research Clinical CenterFederal Siberian Research Clinical CenterFederal Siberian Research Clinical CenterFederal Siberian Research Clinical CenterFederal Siberian Research Clinical CenterFederal Siberian Research Clinical CenterFederal Siberian Research Clinical CenterFederal Siberian Research Clinical CenterThe article describes a clinical case of a female Alzheimer disease patient at an early stage of the neurodegenerative process. The patient did not have any complaints. She was taken to the neuropsychologists by her husband that was concerned because of the patient's family history (his mother-in-law suffered of Alzheimer's disease) and the emergence of some memory problems in his wife. The diagnosis was suspected based on the results of neuropsychological evaluation of cognitive functions which corresponded to mild cognitive impairment. To confirm the presence of a neurodegenerative disease brain positron-emission tomography with F-18 fluorodesoxyglucose (FDG) was performed. Hypometabolism of the imaging agent was detected in the temporal and parietal lobes cortex, in the association cortex of the left temporal and the right occipital lobes, and in the posterior part of the left cyngulate gyrus. This findings correlated with the data of the patients cognitive evaluation and thus provided the nosological diagnosis at an early stage of the disease.https://annaly-nevrologii.com/journal/pathID/article/viewFile/501/392alzheimer's diseaseearly detectionpositron-emission tomography
spellingShingle Semen V. Prokopenko
Boris V. Barankin
Natal'ya М. Mar'ina
Еlena Y. Mozheyko
Аnna F. Bezdenezhnykh
Tat'yana D. Koryagina
Natal'ya G. Chanchikova
Nikolay А. Tokarev
Еlena А. Karlova
Аnastasiya V. Ozerskaya
Еvgeniy А. Badrin
Кirill V. Belugin
Аnastasiya А. Savel'eva
Nikolay V. Shepelevich
PET-CT in early detection of Alzheimer’s disease: а case report
Анналы клинической и экспериментальной неврологии
alzheimer's disease
early detection
positron-emission tomography
title PET-CT in early detection of Alzheimer’s disease: а case report
title_full PET-CT in early detection of Alzheimer’s disease: а case report
title_fullStr PET-CT in early detection of Alzheimer’s disease: а case report
title_full_unstemmed PET-CT in early detection of Alzheimer’s disease: а case report
title_short PET-CT in early detection of Alzheimer’s disease: а case report
title_sort pet ct in early detection of alzheimer s disease а case report
topic alzheimer's disease
early detection
positron-emission tomography
url https://annaly-nevrologii.com/journal/pathID/article/viewFile/501/392
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