Niraparib restrains prostate cancer cell proliferation and metastasis and tumor growth in mice by regulating the lncRNA MEG3/miR-181-5p/GATA6 pathway

Background Poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi), have gained approval for treating patients with castration-resistant prostate cancer (CRPC). Maternally expressed gene 3 (MEG3), a long non-coding RNA (lncRNA), plays a role in inhibiting tumorigenesis through regulating DNA repair g...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs: Ji Cheng, Yi Sun, Huacai Zhao, Wei Ren, Dan Gao, Zhigang Wang, Wei Lv, Qingchuan Dong
Formaat: Artikel
Taal:English
Gepubliceerd in: PeerJ Inc. 2023-11-01
Reeks:PeerJ
Onderwerpen:
Online toegang:https://peerj.com/articles/16314.pdf