Histomorphological responses to aqueous crude leaf extract of Alafia barteri on prefrontal cortex, heart, kidney, liver and testis of adult male Sprague-Dawley rats
Phytonutrients present in Alafia barteri leaves include antioxidants which serves to protect cells and tissues against detrimental effects of reactive oxygen species and other free radicals. This research work was targeted at investigating the activities of oral administration of aqueous leaf extrac...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
TMKarpinski Publisher, Tomasz M. Karpiński
2018-06-01
|
| Series: | European Journal of Biological Research |
| Subjects: | |
| Online Access: | http://www.journals.tmkarpinski.com/index.php/ejbr/article/view/30 |
| _version_ | 1819000309032157184 |
|---|---|
| author | Adelakun Sunday Aderemi Babatunde Ogunlade Olunsegun Dare Omotoso |
| author_facet | Adelakun Sunday Aderemi Babatunde Ogunlade Olunsegun Dare Omotoso |
| author_sort | Adelakun Sunday Aderemi |
| collection | DOAJ |
| description | Phytonutrients present in Alafia barteri leaves include antioxidants which serves to protect cells and tissues against detrimental effects of reactive oxygen species and other free radicals. This research work was targeted at investigating the activities of oral administration of aqueous leaf extract of Alafia barteri on the histology of the prefrontal cortex, heart, kidney, liver and testis of adult Sprague Dawley rats. Twelve (n=12) adult male Sprague Dawley rats weighing between 170-200 g (4-6 weeks old) were used for this study; they were divided into 2 groups of six rats each. The control group A received 2 ml/kg normal saline and treated group B received 500 mg/kg body weight aqueous extract of Alafia barteri for twenty eight days. The gross anatomical parameters of the selected organs and their histology were assessed. The gross anatomical and histological observation of the prefrontal cortex, heart, kidney, liver and testis revealed no visible distortion in Alafia barteri extract treated group when compared with control. Aqueous leaf extract of Alafia barteri thus has no deleterious effects on the histological profile of the prefrontal cortex, heart, kidney, liver and testis of the rats.
DOI: http://dx.doi.org/10.5281/zenodo.1284554 |
| first_indexed | 2024-12-20T22:31:16Z |
| format | Article |
| id | doaj.art-e7fd47e883a34d488b8f2f4befa719ef |
| institution | Directory Open Access Journal |
| issn | 2449-8955 |
| language | English |
| last_indexed | 2024-12-20T22:31:16Z |
| publishDate | 2018-06-01 |
| publisher | TMKarpinski Publisher, Tomasz M. Karpiński |
| record_format | Article |
| series | European Journal of Biological Research |
| spelling | doaj.art-e7fd47e883a34d488b8f2f4befa719ef2022-12-21T19:24:43ZengTMKarpinski Publisher, Tomasz M. KarpińskiEuropean Journal of Biological Research2449-89552018-06-0182Histomorphological responses to aqueous crude leaf extract of Alafia barteri on prefrontal cortex, heart, kidney, liver and testis of adult male Sprague-Dawley ratsAdelakun Sunday Aderemi0Babatunde Ogunlade1Olunsegun Dare Omotoso2Department of Human Anatomy, School of Health and Health Technology, Federal University of Technology, Akure, NigeriaDepartment of Human Anatomy, School of Health and Health Technology, Federal University of Technology, Akure, Ondo State, NigeriaDepartment of Anatomy, Faculty of Basic Medical Sciences, Kogi State University Anyigba, Kogi State, NigeriaPhytonutrients present in Alafia barteri leaves include antioxidants which serves to protect cells and tissues against detrimental effects of reactive oxygen species and other free radicals. This research work was targeted at investigating the activities of oral administration of aqueous leaf extract of Alafia barteri on the histology of the prefrontal cortex, heart, kidney, liver and testis of adult Sprague Dawley rats. Twelve (n=12) adult male Sprague Dawley rats weighing between 170-200 g (4-6 weeks old) were used for this study; they were divided into 2 groups of six rats each. The control group A received 2 ml/kg normal saline and treated group B received 500 mg/kg body weight aqueous extract of Alafia barteri for twenty eight days. The gross anatomical parameters of the selected organs and their histology were assessed. The gross anatomical and histological observation of the prefrontal cortex, heart, kidney, liver and testis revealed no visible distortion in Alafia barteri extract treated group when compared with control. Aqueous leaf extract of Alafia barteri thus has no deleterious effects on the histological profile of the prefrontal cortex, heart, kidney, liver and testis of the rats. DOI: http://dx.doi.org/10.5281/zenodo.1284554http://www.journals.tmkarpinski.com/index.php/ejbr/article/view/30Alafia barteriFrontal cortexHeartKidneyLiverTestis |
| spellingShingle | Adelakun Sunday Aderemi Babatunde Ogunlade Olunsegun Dare Omotoso Histomorphological responses to aqueous crude leaf extract of Alafia barteri on prefrontal cortex, heart, kidney, liver and testis of adult male Sprague-Dawley rats European Journal of Biological Research Alafia barteri Frontal cortex Heart Kidney Liver Testis |
| title | Histomorphological responses to aqueous crude leaf extract of Alafia barteri on prefrontal cortex, heart, kidney, liver and testis of adult male Sprague-Dawley rats |
| title_full | Histomorphological responses to aqueous crude leaf extract of Alafia barteri on prefrontal cortex, heart, kidney, liver and testis of adult male Sprague-Dawley rats |
| title_fullStr | Histomorphological responses to aqueous crude leaf extract of Alafia barteri on prefrontal cortex, heart, kidney, liver and testis of adult male Sprague-Dawley rats |
| title_full_unstemmed | Histomorphological responses to aqueous crude leaf extract of Alafia barteri on prefrontal cortex, heart, kidney, liver and testis of adult male Sprague-Dawley rats |
| title_short | Histomorphological responses to aqueous crude leaf extract of Alafia barteri on prefrontal cortex, heart, kidney, liver and testis of adult male Sprague-Dawley rats |
| title_sort | histomorphological responses to aqueous crude leaf extract of alafia barteri on prefrontal cortex heart kidney liver and testis of adult male sprague dawley rats |
| topic | Alafia barteri Frontal cortex Heart Kidney Liver Testis |
| url | http://www.journals.tmkarpinski.com/index.php/ejbr/article/view/30 |
| work_keys_str_mv | AT adelakunsundayaderemi histomorphologicalresponsestoaqueouscrudeleafextractofalafiabarterionprefrontalcortexheartkidneyliverandtestisofadultmalespraguedawleyrats AT babatundeogunlade histomorphologicalresponsestoaqueouscrudeleafextractofalafiabarterionprefrontalcortexheartkidneyliverandtestisofadultmalespraguedawleyrats AT olunsegundareomotoso histomorphologicalresponsestoaqueouscrudeleafextractofalafiabarterionprefrontalcortexheartkidneyliverandtestisofadultmalespraguedawleyrats |