A case of cribriform carcinoma of the skin: a newly described rare condition
Primary cribriform carcinoma of the skin is an indolent, rare, adnexal tumor. Although its malignant potential remains uncertain, no recurrence or metastasis has been reported. A 33-year-old man presented with a solitary, erythematous, subcutaneous nodule on the right knee. The clinical impression w...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Korean Society of Pathologists & the Korean Society for Cytopathology
2021-01-01
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| Series: | Journal of Pathology and Translational Medicine |
| Subjects: | |
| Online Access: | http://www.jpatholtm.org/upload/pdf/jptm-2020-10-05.pdf |
| _version_ | 1818716732473212928 |
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| author | Hyun Lee Chong-Hyun Won Chan-Sik Park |
| author_facet | Hyun Lee Chong-Hyun Won Chan-Sik Park |
| author_sort | Hyun Lee |
| collection | DOAJ |
| description | Primary cribriform carcinoma of the skin is an indolent, rare, adnexal tumor. Although its malignant potential remains uncertain, no recurrence or metastasis has been reported. A 33-year-old man presented with a solitary, erythematous, subcutaneous nodule on the right knee. The clinical impression was epidermal cyst, and the resected tumor demonstrated a well-circumscribed mass in the dermis and subcutis. The tumor was composed of two regions: a solid component and a cribriform component. The solid component (90%) showed multiple solid nests of epithelial cells. Individual cells had large, oval-to-round, hyperchromatic, pleomorphic nuclei with a nuclear groove. The cribriform component (10%) showed similar neoplastic cells with many prominent lumina. Some lumina had an eosinophilic substance that exhibited a positive periodic acid-Schiff reaction. No recurrence or metastasis was observed within a follow-up period of eight months after excision. In conclusion, we report the first case of primary cribriform carcinoma of the skin in Korea. |
| first_indexed | 2024-12-17T19:23:56Z |
| format | Article |
| id | doaj.art-e7fe87323e9e4d20803670bb37110ba0 |
| institution | Directory Open Access Journal |
| issn | 2383-7837 2383-7845 |
| language | English |
| last_indexed | 2024-12-17T19:23:56Z |
| publishDate | 2021-01-01 |
| publisher | Korean Society of Pathologists & the Korean Society for Cytopathology |
| record_format | Article |
| series | Journal of Pathology and Translational Medicine |
| spelling | doaj.art-e7fe87323e9e4d20803670bb37110ba02022-12-21T21:35:25ZengKorean Society of Pathologists & the Korean Society for CytopathologyJournal of Pathology and Translational Medicine2383-78372383-78452021-01-01551687410.4132/jptm.2020.10.0516944A case of cribriform carcinoma of the skin: a newly described rare conditionHyun Lee0Chong-Hyun Won1Chan-Sik Park2 Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, KoreaPrimary cribriform carcinoma of the skin is an indolent, rare, adnexal tumor. Although its malignant potential remains uncertain, no recurrence or metastasis has been reported. A 33-year-old man presented with a solitary, erythematous, subcutaneous nodule on the right knee. The clinical impression was epidermal cyst, and the resected tumor demonstrated a well-circumscribed mass in the dermis and subcutis. The tumor was composed of two regions: a solid component and a cribriform component. The solid component (90%) showed multiple solid nests of epithelial cells. Individual cells had large, oval-to-round, hyperchromatic, pleomorphic nuclei with a nuclear groove. The cribriform component (10%) showed similar neoplastic cells with many prominent lumina. Some lumina had an eosinophilic substance that exhibited a positive periodic acid-Schiff reaction. No recurrence or metastasis was observed within a follow-up period of eight months after excision. In conclusion, we report the first case of primary cribriform carcinoma of the skin in Korea.http://www.jpatholtm.org/upload/pdf/jptm-2020-10-05.pdfcribriform carcinomaapocrine tumorskin tumor |
| spellingShingle | Hyun Lee Chong-Hyun Won Chan-Sik Park A case of cribriform carcinoma of the skin: a newly described rare condition Journal of Pathology and Translational Medicine cribriform carcinoma apocrine tumor skin tumor |
| title | A case of cribriform carcinoma of the skin: a newly described rare condition |
| title_full | A case of cribriform carcinoma of the skin: a newly described rare condition |
| title_fullStr | A case of cribriform carcinoma of the skin: a newly described rare condition |
| title_full_unstemmed | A case of cribriform carcinoma of the skin: a newly described rare condition |
| title_short | A case of cribriform carcinoma of the skin: a newly described rare condition |
| title_sort | case of cribriform carcinoma of the skin a newly described rare condition |
| topic | cribriform carcinoma apocrine tumor skin tumor |
| url | http://www.jpatholtm.org/upload/pdf/jptm-2020-10-05.pdf |
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