Abnormal activation of genomic LINE1 elements caused by DNA demethylation contributes to lncRNA CASC9 overexpression in esophageal squamous cell carcinoma

Abnormal activation of genomic LINE1 elements caused by DNA demethylation contributes to lncRNA CASC9 overexpression in esophageal squamous cell carcinoma

Long noncoding RNA (lncRNA) cancer susceptibility 9 (CASC9) has been found to be overexpressed and functions as an oncogene in many cancer types. We investigated the molecular mechanism underlying CASC9 overexpression in esophageal squamous cell carcinoma (ESCC). Transcripts containing exons 2 and 6...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Xuedan Chen, Juan Li, Xingying Guan, Yun Bai, Kai Wang
التنسيق:	مقال
اللغة:	English
منشور في:	Elsevier 2024-06-01
سلاسل:	Heliyon
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S2405844024088881

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