A novel SATB1 protein isoform with different biophysical properties

A novel SATB1 protein isoform with different biophysical properties

Intra-thymic T cell development is coordinated by the regulatory actions of SATB1 genome organizer. In this report, we show that SATB1 is involved in the regulation of transcription and splicing, both of which displayed deregulation in Satb1 knockout murine thymocytes. More importantly, we character...

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Bibliographic Details
Main Authors: Tomas Zelenka, Dionysios-Alexandros Papamatheakis, Petros Tzerpos, Giorgos Panagopoulos, Konstantinos C. Tsolis, Vassilis M. Papadakis, Dimitris Mariatos Metaxas, George Papadogkonas, Eleftherios Mores, Manouela Kapsetaki, Joseph Papamatheakis, David Stanek, Charalampos Spilianakis
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
SATB1
T cells
chromatin organization
prion
phase separation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1242481/full

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