Crop protection practices and risks associated with human fungal infectious diseases: a One Health perspective
We review interactions between crop protection practices (developed to control plant pathogens and invertebrate pests) and human fungal infectious diseases. Unlike viral, bacterial and parasitic infections, fungal infections in humans are usually only superficial in healthy individuals, but can beco...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
EDP Sciences
2023-01-01
|
| Series: | Cahiers Agricultures |
| Subjects: | |
| Online Access: | https://www.cahiersagricultures.fr/articles/cagri/full_html/2023/01/cagri220090/cagri220090.html |
| _version_ | 1797901702017318912 |
|---|---|
| author | Ratnadass Alain Sester Mathilde |
| author_facet | Ratnadass Alain Sester Mathilde |
| author_sort | Ratnadass Alain |
| collection | DOAJ |
| description | We review interactions between crop protection practices (developed to control plant pathogens and invertebrate pests) and human fungal infectious diseases. Unlike viral, bacterial and parasitic infections, fungal infections in humans are usually only superficial in healthy individuals, but can become invasive and pose serious risks to immunosuppressed individuals. Although their global impact is less than that of other infectious diseases, human fungal infections still pose serious public health issues. For instance, the use of synthetic agricultural fungicides, particularly the azole class, under conventional intensive, or efficiency improvement-based crop protection practices, is at risk as far as antimicrobial resistance is concerned, due to cases of cross-resistance to clinical azoles used to treat pulmonary aspergillosis, candidiasis and cryptococcocis. In this respect, the One Health approach, originally designed for other types of human pathogens, looks relevant for human pathogenic fungi. Additionally, some entomopathogenic fungi used as biocontrol products against crop pests in a substitution-based approach, may be potentially pathogenic to humans. Very few examples of redesign-based practices (i.e. Agroecological Crop Protection) emerged from our analysis on human fungal diseases. However, discontinuing agricultural azole fungicides (as practiced on organic farms, and which may to some extent be related to the redesign strategy) appears to be the best way to reduce selection pressure and hence the level of azole-resistant human pathogenic fungal strains in the environment. |
| first_indexed | 2024-04-10T09:06:03Z |
| format | Article |
| id | doaj.art-e8038899264e4af2b05da70e81ca3dbd |
| institution | Directory Open Access Journal |
| issn | 1166-7699 1777-5949 |
| language | English |
| last_indexed | 2024-04-10T09:06:03Z |
| publishDate | 2023-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | Cahiers Agricultures |
| spelling | doaj.art-e8038899264e4af2b05da70e81ca3dbd2023-02-21T08:05:20ZengEDP SciencesCahiers Agricultures1166-76991777-59492023-01-0132710.1051/cagri/2022036cagri220090Crop protection practices and risks associated with human fungal infectious diseases: a One Health perspectiveRatnadass Alain0https://orcid.org/0000-0002-8873-5671Sester Mathilde1https://orcid.org/0000-0002-2329-9119CIRAD, UPR AïdaAïda, Univ Montpellier, CIRADWe review interactions between crop protection practices (developed to control plant pathogens and invertebrate pests) and human fungal infectious diseases. Unlike viral, bacterial and parasitic infections, fungal infections in humans are usually only superficial in healthy individuals, but can become invasive and pose serious risks to immunosuppressed individuals. Although their global impact is less than that of other infectious diseases, human fungal infections still pose serious public health issues. For instance, the use of synthetic agricultural fungicides, particularly the azole class, under conventional intensive, or efficiency improvement-based crop protection practices, is at risk as far as antimicrobial resistance is concerned, due to cases of cross-resistance to clinical azoles used to treat pulmonary aspergillosis, candidiasis and cryptococcocis. In this respect, the One Health approach, originally designed for other types of human pathogens, looks relevant for human pathogenic fungi. Additionally, some entomopathogenic fungi used as biocontrol products against crop pests in a substitution-based approach, may be potentially pathogenic to humans. Very few examples of redesign-based practices (i.e. Agroecological Crop Protection) emerged from our analysis on human fungal diseases. However, discontinuing agricultural azole fungicides (as practiced on organic farms, and which may to some extent be related to the redesign strategy) appears to be the best way to reduce selection pressure and hence the level of azole-resistant human pathogenic fungal strains in the environment.https://www.cahiersagricultures.fr/articles/cagri/full_html/2023/01/cagri220090/cagri220090.htmlantimicrobial resistanceaspergillosisazolescandidiasisplant protection |
| spellingShingle | Ratnadass Alain Sester Mathilde Crop protection practices and risks associated with human fungal infectious diseases: a One Health perspective Cahiers Agricultures antimicrobial resistance aspergillosis azoles candidiasis plant protection |
| title | Crop protection practices and risks associated with human fungal infectious diseases: a One Health perspective |
| title_full | Crop protection practices and risks associated with human fungal infectious diseases: a One Health perspective |
| title_fullStr | Crop protection practices and risks associated with human fungal infectious diseases: a One Health perspective |
| title_full_unstemmed | Crop protection practices and risks associated with human fungal infectious diseases: a One Health perspective |
| title_short | Crop protection practices and risks associated with human fungal infectious diseases: a One Health perspective |
| title_sort | crop protection practices and risks associated with human fungal infectious diseases a one health perspective |
| topic | antimicrobial resistance aspergillosis azoles candidiasis plant protection |
| url | https://www.cahiersagricultures.fr/articles/cagri/full_html/2023/01/cagri220090/cagri220090.html |
| work_keys_str_mv | AT ratnadassalain cropprotectionpracticesandrisksassociatedwithhumanfungalinfectiousdiseasesaonehealthperspective AT sestermathilde cropprotectionpracticesandrisksassociatedwithhumanfungalinfectiousdiseasesaonehealthperspective |