Contribution of Janus-Kinase/Signal Transduction Activator of Transcription Pathway in the Pathogenesis of Vasculitis: A Possible Treatment Target in the Upcoming Future

Contribution of Janus-Kinase/Signal Transduction Activator of Transcription Pathway in the Pathogenesis of Vasculitis: A Possible Treatment Target in the Upcoming Future

Janus-kinase (JAK) and signal transduction activator of transcription (STAT) signal transduction pathway is involved in a wide range of physiological and pathological processes, including in the pathogenesis of several autoimmune diseases. Data supporting the role of JAK/STAT in the development of v...

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Bibliographic Details
Main Authors: Roberto Bursi, Giacomo Cafaro, Carlo Perricone, Ilenia Riccucci, Santina Calvacchi, Roberto Gerli, Elena Bartoloni
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pharmacology
Subjects:
JAK/STAT
vasculitis
giant cell arteritis
Takayasu arteritis
Behçet’s disease
JAK inhibitors
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.635663/full

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