Effect of ectopic high expression of transcription factor OCT4 on the “stemness” characteristics of human bone marrow-derived mesenchymal stromal cells

Effect of ectopic high expression of transcription factor OCT4 on the “stemness” characteristics of human bone marrow-derived mesenchymal stromal cells

Abstract Objective To investigate the effect of ectopic high expression of OCT4 on the stemness characteristics of bone marrow-derived mesenchymal stromal cells (BM-MSCs). Methods BM-MSCs were collected from three de novo acute lymphoblastic leukemia (ALL) and three aplastic anemia patients (AA), wh...

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Bibliographic Details
Main Authors: Xiaoping Guo, Yongmin Tang, Ping Zhang, Sisi Li, Yuanyuan Chen, Baiqin Qian, Hongqiang Shen, Ning Zhao
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Stem Cell Research & Therapy
Subjects:
Transcription factor
OCT4
Overexpression
Bone marrow-derived MSCs
Stemness
Online Access:http://link.springer.com/article/10.1186/s13287-019-1263-4

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