Dysregulation of Alzheimer’s disease-related genes and proteins following cardiac arrest

Cardiac arrest, usually occurring in the aged population, is the most important cause of high morbidity and death in developed countries. Commonly, attention, depression, cognitive impairment, spatial memory, short- and long-term memory, executive functions, decreased quality of life and social part...

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Main Authors: Ryszard Pluta, Marzena Ułamek-Kozioł, Sławomir Januszewski, Stanisław J. Czuczwar
Format: Article
Language:English
Published: Termedia Publishing House 2017-12-01
Series:Folia Neuropathologica
Subjects:
Online Access:https://www.termedia.pl/Dysregulation-of-Alzheimer-s-disease-related-genes-and-proteins-following-cardiac-arrest,20,31344,1,1.html
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author Ryszard Pluta
Marzena Ułamek-Kozioł
Sławomir Januszewski
Stanisław J. Czuczwar
author_facet Ryszard Pluta
Marzena Ułamek-Kozioł
Sławomir Januszewski
Stanisław J. Czuczwar
author_sort Ryszard Pluta
collection DOAJ
description Cardiac arrest, usually occurring in the aged population, is the most important cause of high morbidity and death in developed countries. Commonly, attention, depression, cognitive impairment, spatial memory, short- and long-term memory, executive functions, decreased quality of life and social participation are disturbed following circulation arrest. Deficits in cognitive function, similar to prodromal Alzheimer’s disease dementia, following cardiac arrest remain an area of concern. Recent research has focused on the post-resuscitation period to identify mechanisms of long-term brain damage and cognitive impairment. As more patients survive longer periods after cardiac arrest, attention is focused on interventions that may enhance cognitive and psychosocial perceptions. Here, we review the new data influencing the cognitive and functional outcome in the post-resuscitation period.
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spelling doaj.art-e8150e7deacd4bd2a06e2a33eeab03312022-12-22T03:05:58ZengTermedia Publishing HouseFolia Neuropathologica1641-46401509-572X2017-12-0155428328810.5114/fn.2017.7238431344Dysregulation of Alzheimer’s disease-related genes and proteins following cardiac arrestRyszard PlutaMarzena Ułamek-KoziołSławomir JanuszewskiStanisław J. CzuczwarCardiac arrest, usually occurring in the aged population, is the most important cause of high morbidity and death in developed countries. Commonly, attention, depression, cognitive impairment, spatial memory, short- and long-term memory, executive functions, decreased quality of life and social participation are disturbed following circulation arrest. Deficits in cognitive function, similar to prodromal Alzheimer’s disease dementia, following cardiac arrest remain an area of concern. Recent research has focused on the post-resuscitation period to identify mechanisms of long-term brain damage and cognitive impairment. As more patients survive longer periods after cardiac arrest, attention is focused on interventions that may enhance cognitive and psychosocial perceptions. Here, we review the new data influencing the cognitive and functional outcome in the post-resuscitation period.https://www.termedia.pl/Dysregulation-of-Alzheimer-s-disease-related-genes-and-proteins-following-cardiac-arrest,20,31344,1,1.html<i>cardiac arrest brain ischemia Alzheimer’s disease genes proteins</i>
spellingShingle Ryszard Pluta
Marzena Ułamek-Kozioł
Sławomir Januszewski
Stanisław J. Czuczwar
Dysregulation of Alzheimer’s disease-related genes and proteins following cardiac arrest
Folia Neuropathologica
<i>cardiac arrest
brain ischemia
Alzheimer’s disease
genes
proteins</i>
title Dysregulation of Alzheimer’s disease-related genes and proteins following cardiac arrest
title_full Dysregulation of Alzheimer’s disease-related genes and proteins following cardiac arrest
title_fullStr Dysregulation of Alzheimer’s disease-related genes and proteins following cardiac arrest
title_full_unstemmed Dysregulation of Alzheimer’s disease-related genes and proteins following cardiac arrest
title_short Dysregulation of Alzheimer’s disease-related genes and proteins following cardiac arrest
title_sort dysregulation of alzheimer s disease related genes and proteins following cardiac arrest
topic <i>cardiac arrest
brain ischemia
Alzheimer’s disease
genes
proteins</i>
url https://www.termedia.pl/Dysregulation-of-Alzheimer-s-disease-related-genes-and-proteins-following-cardiac-arrest,20,31344,1,1.html
work_keys_str_mv AT ryszardpluta dysregulationofalzheimersdiseaserelatedgenesandproteinsfollowingcardiacarrest
AT marzenaułamekkozioł dysregulationofalzheimersdiseaserelatedgenesandproteinsfollowingcardiacarrest
AT sławomirjanuszewski dysregulationofalzheimersdiseaserelatedgenesandproteinsfollowingcardiacarrest
AT stanisławjczuczwar dysregulationofalzheimersdiseaserelatedgenesandproteinsfollowingcardiacarrest