A rare case of Candida parapsilosis osteomyelitis: a literature review and proposed treatment algorithm
Abstract Background Candida parapsilosis is a rare opportunistic pathogen that can be found in immunosuppressed patients. There are seldom-reported cases of fungal osteomyelitis surrounding orthopedic implants. Case presentation This is a case of chronic Candida parapsilosis osteomyelitis in an immu...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-12-01
|
| Series: | Patient Safety in Surgery |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13037-017-0146-9 |
| _version_ | 1818213866073489408 |
|---|---|
| author | John Michael Yingling Li Sun Richard Yoon Frank Liporace |
| author_facet | John Michael Yingling Li Sun Richard Yoon Frank Liporace |
| author_sort | John Michael Yingling |
| collection | DOAJ |
| description | Abstract Background Candida parapsilosis is a rare opportunistic pathogen that can be found in immunosuppressed patients. There are seldom-reported cases of fungal osteomyelitis surrounding orthopedic implants. Case presentation This is a case of chronic Candida parapsilosis osteomyelitis in an immunocompromised patient with a prior open reduction and internal fixation for a closed bimalleolar ankle fracture that went on to neglected wound complications. The patient underwent series of treatments including removal of hardware, serial irrigation and debridements, negative pressure wound therapy, and intravenous antifungal therapy. Our case illustrates the possibility of this rare pathogen involved in orthopedic surgery particularly in immunocompromised hosts. Conclusion Fungal and atypical pathogens should always be considered in such patients or if another diagnosis is not clear. Protracted time to culture specimens should be considered for at least four weeks in such situations. This article outlines a review of the literature and treatment algorithm to guide physicians when managing patients with this rare infection. |
| first_indexed | 2024-12-12T06:11:05Z |
| format | Article |
| id | doaj.art-e8155ae49dfe4d009311f58264c5e4fd |
| institution | Directory Open Access Journal |
| issn | 1754-9493 |
| language | English |
| last_indexed | 2024-12-12T06:11:05Z |
| publishDate | 2017-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Patient Safety in Surgery |
| spelling | doaj.art-e8155ae49dfe4d009311f58264c5e4fd2022-12-22T00:35:10ZengBMCPatient Safety in Surgery1754-94932017-12-011111510.1186/s13037-017-0146-9A rare case of Candida parapsilosis osteomyelitis: a literature review and proposed treatment algorithmJohn Michael Yingling0Li Sun1Richard Yoon2Frank Liporace3Division of Orthopaedic Trauma & Adult Reconstruction, Department of Orthopaedic Surgery, Jersey City Medical Center – RWJBarnabas HealthDivision of Orthopaedic Trauma & Adult Reconstruction, Department of Orthopaedic Surgery, Jersey City Medical Center – RWJBarnabas HealthDivision of Orthopaedic Trauma & Adult Reconstruction, Department of Orthopaedic Surgery, Jersey City Medical Center – RWJBarnabas HealthDivision of Orthopaedic Trauma & Adult Reconstruction, Department of Orthopaedic Surgery, Jersey City Medical Center – RWJBarnabas HealthAbstract Background Candida parapsilosis is a rare opportunistic pathogen that can be found in immunosuppressed patients. There are seldom-reported cases of fungal osteomyelitis surrounding orthopedic implants. Case presentation This is a case of chronic Candida parapsilosis osteomyelitis in an immunocompromised patient with a prior open reduction and internal fixation for a closed bimalleolar ankle fracture that went on to neglected wound complications. The patient underwent series of treatments including removal of hardware, serial irrigation and debridements, negative pressure wound therapy, and intravenous antifungal therapy. Our case illustrates the possibility of this rare pathogen involved in orthopedic surgery particularly in immunocompromised hosts. Conclusion Fungal and atypical pathogens should always be considered in such patients or if another diagnosis is not clear. Protracted time to culture specimens should be considered for at least four weeks in such situations. This article outlines a review of the literature and treatment algorithm to guide physicians when managing patients with this rare infection.http://link.springer.com/article/10.1186/s13037-017-0146-9Acute and chronic deep fungal infection managementExposed hardwareFungusIrrigation and debridementNegative pressure wound therapyRemoval of hardware |
| spellingShingle | John Michael Yingling Li Sun Richard Yoon Frank Liporace A rare case of Candida parapsilosis osteomyelitis: a literature review and proposed treatment algorithm Patient Safety in Surgery Acute and chronic deep fungal infection management Exposed hardware Fungus Irrigation and debridement Negative pressure wound therapy Removal of hardware |
| title | A rare case of Candida parapsilosis osteomyelitis: a literature review and proposed treatment algorithm |
| title_full | A rare case of Candida parapsilosis osteomyelitis: a literature review and proposed treatment algorithm |
| title_fullStr | A rare case of Candida parapsilosis osteomyelitis: a literature review and proposed treatment algorithm |
| title_full_unstemmed | A rare case of Candida parapsilosis osteomyelitis: a literature review and proposed treatment algorithm |
| title_short | A rare case of Candida parapsilosis osteomyelitis: a literature review and proposed treatment algorithm |
| title_sort | rare case of candida parapsilosis osteomyelitis a literature review and proposed treatment algorithm |
| topic | Acute and chronic deep fungal infection management Exposed hardware Fungus Irrigation and debridement Negative pressure wound therapy Removal of hardware |
| url | http://link.springer.com/article/10.1186/s13037-017-0146-9 |
| work_keys_str_mv | AT johnmichaelyingling ararecaseofcandidaparapsilosisosteomyelitisaliteraturereviewandproposedtreatmentalgorithm AT lisun ararecaseofcandidaparapsilosisosteomyelitisaliteraturereviewandproposedtreatmentalgorithm AT richardyoon ararecaseofcandidaparapsilosisosteomyelitisaliteraturereviewandproposedtreatmentalgorithm AT frankliporace ararecaseofcandidaparapsilosisosteomyelitisaliteraturereviewandproposedtreatmentalgorithm AT johnmichaelyingling rarecaseofcandidaparapsilosisosteomyelitisaliteraturereviewandproposedtreatmentalgorithm AT lisun rarecaseofcandidaparapsilosisosteomyelitisaliteraturereviewandproposedtreatmentalgorithm AT richardyoon rarecaseofcandidaparapsilosisosteomyelitisaliteraturereviewandproposedtreatmentalgorithm AT frankliporace rarecaseofcandidaparapsilosisosteomyelitisaliteraturereviewandproposedtreatmentalgorithm |