Characterization of a novel model for atherosclerosis imaging: the apolipoprotein E-deficient rat

Characterization of a novel model for atherosclerosis imaging: the apolipoprotein E-deficient rat

Abstract Background The apolipoprotein E-deficient (apoE −/− ) mouse is a well-established model for studying atherosclerosis. However, its small size limits its use in longitudinal positron emission tomography (PET) imaging studies. Recently, the apoE −/− rat has emerged as an alternative. With thi...

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Bibliographic Details
Main Authors: Jürgen W. A. Sijbesma, Aren van Waarde, Sebastiaan Kristensen, Ilse Kion, Uwe J. F. Tietge, Jan-Luuk Hillebrands, Marian L. C. Bulthuis, Hendrik Buikema, Dalibor Nakladal, Marit Westerterp, Fan Liu, Hendrikus H. Boersma, Rudi A. J. O. Dierckx, Riemer H. J. A. Slart
Format: Article
Language:English
Published: SpringerOpen 2023-12-01
Series:EJNMMI Research
Subjects:
Apolipoprotein E-deficient rat
Atherosclerosis
[18F]2-fluoro-2-deoxy-D-glucose
Positron emission tomography (PET)
Online Access:https://doi.org/10.1186/s13550-023-01055-5

Internet

https://doi.org/10.1186/s13550-023-01055-5

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