Gut–Liver Axis and Inflammasome Activation in Cholangiocyte Pathophysiology

Gut–Liver Axis and Inflammasome Activation in Cholangiocyte Pathophysiology

The Nlrp3 inflammasome is a multiprotein complex activated by a number of bacterial products or danger signals and is involved in the regulation of inflammatory processes through caspase-1 activation. The Nlrp3 is expressed in immune cells but also in hepatocytes and cholangiocytes, where it appears...

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Bibliographic Details
Main Authors: Luca Maroni, Elisabetta Ninfole, Claudio Pinto, Antonio Benedetti, Marco Marzioni
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
inflammasome
nlrp3
cholangiocyte
gut–liver axis
Online Access:https://www.mdpi.com/2073-4409/9/3/736

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