Synthesis and Pharmacological Evaluation of Some New Pyrimidine Derivatives Containing 1,2,4-Triazole

Synthesis and Pharmacological Evaluation of Some New Pyrimidine Derivatives Containing 1,2,4-Triazole

Purpose: An efficient method has been described for synthesis of 6-(substituted aryl)-4-(3,5-diphenyl-1H-1,2,4-triazol-1-yl)-1, 6-dihydropyrimidine-2-thiol, as a beneficial antimicrobial, anticonvulsant and anticancer agents. Methods: The clalcones of title compounds were synthesized in three steps...

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Bibliographic Details
Main Authors:	Shantaram Gajanan Khanage, S. Appala Raju, Popat Baban Mohite, Ramdas Bhanudas Pandhare
Format:	Article
Language:	English
Published:	Tabriz University of Medical Sciences 2012-08-01
Series:	Advanced Pharmaceutical Bulletin
Subjects:	Chalcones Condensation Dihydropyrimidine Antimicrobial activity MES activity Antitumor agent
Online Access:	http://journals.tbzmed.ac.ir/PDF/APB/Manuscript/APB-2-213.pdf

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