pATM and γH2AX are effective radiation biomarkers in assessing the radiosensitivity of 12C6+ in human tumor cells

pATM and γH2AX are effective radiation biomarkers in assessing the radiosensitivity of 12C6+ in human tumor cells

Abstract Background Tumour radiosensitivity would be particularly useful in optimizing the radiation dose during radiotherapy. The aim of the current study was to evaluate the potential value of phosphorylated H2AX (γH2AX) and ATM (pATM) in assessing 12C6+ radiosensitivity of tumour cells. Methods H...

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Bibliographic Details
Main Authors: Jin Zhao, Zhong Guo, Shuyan Pei, Lei Song, Chenjing Wang, Jianxiu Ma, Long Jin, Yanqing Ma, Renke He, Jianbin Zhong, Ying Ma, Hong Zhang
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Cancer Cell International
Subjects:
12C6+
Human tumor cells
Survival fraction
γH2AX
ATM
Online Access:http://link.springer.com/article/10.1186/s12935-017-0419-5

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