Clinical and biochemical profile of lean type 2 diabetes mellitus

Background: Type 2 diabetes mellitus is the most prevalent form of diabetes worldwide. In western countries majority of the cases are obese. The scenario may be different in certain parts of India. Various studies have reported a high prevalence of lean type 2 diabetes mellitus with a body mass inde...

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Main Authors: Punyakrit Deb Barma, Salam Ranabir, Lallan Prasad, Thangjam Premchand Singh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Indian Journal of Endocrinology and Metabolism
Subjects:
Online Access:http://www.ijem.in/article.asp?issn=2230-8210;year=2011;volume=15;issue=5;spage=40;epage=43;aulast=Barma
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author Punyakrit Deb Barma
Salam Ranabir
Lallan Prasad
Thangjam Premchand Singh
author_facet Punyakrit Deb Barma
Salam Ranabir
Lallan Prasad
Thangjam Premchand Singh
author_sort Punyakrit Deb Barma
collection DOAJ
description Background: Type 2 diabetes mellitus is the most prevalent form of diabetes worldwide. In western countries majority of the cases are obese. The scenario may be different in certain parts of India. Various studies have reported a high prevalence of lean type 2 diabetes mellitus with a body mass index < 19 kg/m 2 . Materials and Methods: We evaluated 100 cases of lean type 2 diabetes mellitus (62 males and 38 females). Results and Conclusion: The mean duration of diabetes was 51.7 months (range 5-180 months). The glycemic control was poor according to standard guidelines. The majority of them showed response to oral hypoglycemic agents. Secondary failure to oral hypoglycemic agents was seen in 27 patients. The prevalence of microvascular complications was much higher than macrovascular complications. Neuropathy was the commonest complication seen in 70%, followed by retinopathy in 25%. Only 12 patients had hypertension, one had coronary artery disease and two had cerebrovascular accident. Lipid profile was not significantly deranged in our patients.
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spelling doaj.art-e81d0d9e96734bb8b5279aba9e1945162022-12-21T22:04:15ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102230-95002011-01-01155404310.4103/2230-8210.83061Clinical and biochemical profile of lean type 2 diabetes mellitusPunyakrit Deb BarmaSalam RanabirLallan PrasadThangjam Premchand SinghBackground: Type 2 diabetes mellitus is the most prevalent form of diabetes worldwide. In western countries majority of the cases are obese. The scenario may be different in certain parts of India. Various studies have reported a high prevalence of lean type 2 diabetes mellitus with a body mass index < 19 kg/m 2 . Materials and Methods: We evaluated 100 cases of lean type 2 diabetes mellitus (62 males and 38 females). Results and Conclusion: The mean duration of diabetes was 51.7 months (range 5-180 months). The glycemic control was poor according to standard guidelines. The majority of them showed response to oral hypoglycemic agents. Secondary failure to oral hypoglycemic agents was seen in 27 patients. The prevalence of microvascular complications was much higher than macrovascular complications. Neuropathy was the commonest complication seen in 70%, followed by retinopathy in 25%. Only 12 patients had hypertension, one had coronary artery disease and two had cerebrovascular accident. Lipid profile was not significantly deranged in our patients.http://www.ijem.in/article.asp?issn=2230-8210;year=2011;volume=15;issue=5;spage=40;epage=43;aulast=BarmaLean type diabetesmellitusmacrovasuclarmicrovascular
spellingShingle Punyakrit Deb Barma
Salam Ranabir
Lallan Prasad
Thangjam Premchand Singh
Clinical and biochemical profile of lean type 2 diabetes mellitus
Indian Journal of Endocrinology and Metabolism
Lean type diabetesmellitus
macrovasuclar
microvascular
title Clinical and biochemical profile of lean type 2 diabetes mellitus
title_full Clinical and biochemical profile of lean type 2 diabetes mellitus
title_fullStr Clinical and biochemical profile of lean type 2 diabetes mellitus
title_full_unstemmed Clinical and biochemical profile of lean type 2 diabetes mellitus
title_short Clinical and biochemical profile of lean type 2 diabetes mellitus
title_sort clinical and biochemical profile of lean type 2 diabetes mellitus
topic Lean type diabetesmellitus
macrovasuclar
microvascular
url http://www.ijem.in/article.asp?issn=2230-8210;year=2011;volume=15;issue=5;spage=40;epage=43;aulast=Barma
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AT thangjampremchandsingh clinicalandbiochemicalprofileofleantype2diabetesmellitus