Study of correlation between epicardial fat thickness and severity of coronary artery disease
Epicardial fat thickness (EFT) reflects visceral adiposity and is associated with coronary artery disease (CAD). This study aimed to assess the correlation of echocardiographic EFT with the severity of CAD and to determine the EFT cut-off to predict CAD. EFT was measured in 503 patients undergoing c...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-09-01
|
| Series: | Indian Heart Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0019483220301723 |
| _version_ | 1819098814683807744 |
|---|---|
| author | Sunil Kumar Shambu Nagaraj Desai Nikhil Sundaresh M. Suresh Babu B. Madhu Oliver Joel Gona |
| author_facet | Sunil Kumar Shambu Nagaraj Desai Nikhil Sundaresh M. Suresh Babu B. Madhu Oliver Joel Gona |
| author_sort | Sunil Kumar Shambu |
| collection | DOAJ |
| description | Epicardial fat thickness (EFT) reflects visceral adiposity and is associated with coronary artery disease (CAD). This study aimed to assess the correlation of echocardiographic EFT with the severity of CAD and to determine the EFT cut-off to predict CAD. EFT was measured in 503 patients undergoing coronary angiogram. Mean EFT was significantly higher in the CAD group than control group (5.55 ± 1.21 mm vs 3.25 ± 1.15 mm, p < 0.0001). EFT correlated with Gensini score (r = 0.906, p < 0.001). EFT cut-off ≥ 4.75 mm had 87% sensitivity and 63% specificity for prediction of significant CAD (AUC: 0.831, p < 0.001). |
| first_indexed | 2024-12-22T00:36:58Z |
| format | Article |
| id | doaj.art-e8205c3c08ef4e89ad4af9346377625d |
| institution | Directory Open Access Journal |
| issn | 0019-4832 |
| language | English |
| last_indexed | 2024-12-22T00:36:58Z |
| publishDate | 2020-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Indian Heart Journal |
| spelling | doaj.art-e8205c3c08ef4e89ad4af9346377625d2022-12-21T18:44:47ZengElsevierIndian Heart Journal0019-48322020-09-01725445447Study of correlation between epicardial fat thickness and severity of coronary artery diseaseSunil Kumar Shambu0Nagaraj Desai1Nikhil Sundaresh2M. Suresh Babu3B. Madhu4Oliver Joel Gona5Head, Department of Cardiology, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, SS Nagar, Mysore 15, India; Corresponding author. Head, Department of Cardiology, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, SS Nagar, Mysore – 15, India.Department of Cardiology, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, SS Nagar, Mysore 15, IndiaDept. of Medicine, AJ Institute of Medical Sciences, Mangalore, IndiaJSS Medical College and Hospital, JSS Academy of Higher Education and Research, SS Nagar, Mysore, 15, IndiaDepartment of Community Medicine, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, SS Nagar, Mysore 15, IndiaDepartment of Pharmacy Practice, JSS College of Pharmacy, JSS Academy of Higher Education and Research, SS Nagar, Mysore 15, IndiaEpicardial fat thickness (EFT) reflects visceral adiposity and is associated with coronary artery disease (CAD). This study aimed to assess the correlation of echocardiographic EFT with the severity of CAD and to determine the EFT cut-off to predict CAD. EFT was measured in 503 patients undergoing coronary angiogram. Mean EFT was significantly higher in the CAD group than control group (5.55 ± 1.21 mm vs 3.25 ± 1.15 mm, p < 0.0001). EFT correlated with Gensini score (r = 0.906, p < 0.001). EFT cut-off ≥ 4.75 mm had 87% sensitivity and 63% specificity for prediction of significant CAD (AUC: 0.831, p < 0.001).http://www.sciencedirect.com/science/article/pii/S0019483220301723Epicardial fat thicknessEchocardiographyGensini scoreCoronary artery disease |
| spellingShingle | Sunil Kumar Shambu Nagaraj Desai Nikhil Sundaresh M. Suresh Babu B. Madhu Oliver Joel Gona Study of correlation between epicardial fat thickness and severity of coronary artery disease Indian Heart Journal Epicardial fat thickness Echocardiography Gensini score Coronary artery disease |
| title | Study of correlation between epicardial fat thickness and severity of coronary artery disease |
| title_full | Study of correlation between epicardial fat thickness and severity of coronary artery disease |
| title_fullStr | Study of correlation between epicardial fat thickness and severity of coronary artery disease |
| title_full_unstemmed | Study of correlation between epicardial fat thickness and severity of coronary artery disease |
| title_short | Study of correlation between epicardial fat thickness and severity of coronary artery disease |
| title_sort | study of correlation between epicardial fat thickness and severity of coronary artery disease |
| topic | Epicardial fat thickness Echocardiography Gensini score Coronary artery disease |
| url | http://www.sciencedirect.com/science/article/pii/S0019483220301723 |
| work_keys_str_mv | AT sunilkumarshambu studyofcorrelationbetweenepicardialfatthicknessandseverityofcoronaryarterydisease AT nagarajdesai studyofcorrelationbetweenepicardialfatthicknessandseverityofcoronaryarterydisease AT nikhilsundaresh studyofcorrelationbetweenepicardialfatthicknessandseverityofcoronaryarterydisease AT msureshbabu studyofcorrelationbetweenepicardialfatthicknessandseverityofcoronaryarterydisease AT bmadhu studyofcorrelationbetweenepicardialfatthicknessandseverityofcoronaryarterydisease AT oliverjoelgona studyofcorrelationbetweenepicardialfatthicknessandseverityofcoronaryarterydisease |