<i>Candida tropicalis</i> endocarditis: Treatment in a resource-poor setting
Fungal endocarditis (FE) is rare in children and does not usually occur in structurally normal hearts. The commonest causative agent is <i>Candida albicans</i>. We report a 5-year-old female child presenting with high-grade fever and cardiac failure. Anemia, leukocytosis and high CRP wer...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2010-01-01
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| Series: | Annals of Pediatric Cardiology |
| Subjects: | |
| Online Access: | http://www.annalspc.com/article.asp?issn=0974-2069;year=2010;volume=3;issue=2;spage=174;epage=177;aulast=Kumar |
| _version_ | 1818011761573363712 |
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| author | Kumar Prashant Muranjan Mamta Tullu Milind Vaideeswar Pradeep Kher Archana Lahiri Keya |
| author_facet | Kumar Prashant Muranjan Mamta Tullu Milind Vaideeswar Pradeep Kher Archana Lahiri Keya |
| author_sort | Kumar Prashant |
| collection | DOAJ |
| description | Fungal endocarditis (FE) is rare in children and does not usually occur in structurally normal hearts. The commonest causative agent is <i>Candida albicans</i>. We report a 5-year-old female child presenting with high-grade fever and cardiac failure. Anemia, leukocytosis and high CRP were found, but bacterial blood culture was sterile. There was no response to antimicrobial agents. Two-dimensional echocardiography revealed a large heterogeneous mass attached to the right ventricle and tricuspid valve. Provisional diagnosis of FE was made, which was confirmed by growth of <i>Candida tropicalis</i> in blood culture. Liposomal amphotericin B was started, followed by radical curative surgery including excision of the entire vegetation with total tricuspid valve excision. Histopathology and culture of the resected vegetation confirmed the diagnosis. The patient was given antifungal therapy for a total of 7 weeks, including 2 weeks of post-operative treatment, following which she was afebrile. |
| first_indexed | 2024-04-14T06:12:43Z |
| format | Article |
| id | doaj.art-e8211d51a7b9490eaf790dc2bc01c137 |
| institution | Directory Open Access Journal |
| issn | 0974-2069 0974-5149 |
| language | English |
| last_indexed | 2024-04-14T06:12:43Z |
| publishDate | 2010-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Pediatric Cardiology |
| spelling | doaj.art-e8211d51a7b9490eaf790dc2bc01c1372022-12-22T02:08:20ZengWolters Kluwer Medknow PublicationsAnnals of Pediatric Cardiology0974-20690974-51492010-01-0132174177<i>Candida tropicalis</i> endocarditis: Treatment in a resource-poor settingKumar PrashantMuranjan MamtaTullu MilindVaideeswar PradeepKher ArchanaLahiri KeyaFungal endocarditis (FE) is rare in children and does not usually occur in structurally normal hearts. The commonest causative agent is <i>Candida albicans</i>. We report a 5-year-old female child presenting with high-grade fever and cardiac failure. Anemia, leukocytosis and high CRP were found, but bacterial blood culture was sterile. There was no response to antimicrobial agents. Two-dimensional echocardiography revealed a large heterogeneous mass attached to the right ventricle and tricuspid valve. Provisional diagnosis of FE was made, which was confirmed by growth of <i>Candida tropicalis</i> in blood culture. Liposomal amphotericin B was started, followed by radical curative surgery including excision of the entire vegetation with total tricuspid valve excision. Histopathology and culture of the resected vegetation confirmed the diagnosis. The patient was given antifungal therapy for a total of 7 weeks, including 2 weeks of post-operative treatment, following which she was afebrile.http://www.annalspc.com/article.asp?issn=0974-2069;year=2010;volume=3;issue=2;spage=174;epage=177;aulast=KumarAmphotericin B<i>Candida tropicalis</i>fungal endocarditistricuspid valve |
| spellingShingle | Kumar Prashant Muranjan Mamta Tullu Milind Vaideeswar Pradeep Kher Archana Lahiri Keya <i>Candida tropicalis</i> endocarditis: Treatment in a resource-poor setting Annals of Pediatric Cardiology Amphotericin B <i>Candida tropicalis</i> fungal endocarditis tricuspid valve |
| title | <i>Candida tropicalis</i> endocarditis: Treatment in a resource-poor setting |
| title_full | <i>Candida tropicalis</i> endocarditis: Treatment in a resource-poor setting |
| title_fullStr | <i>Candida tropicalis</i> endocarditis: Treatment in a resource-poor setting |
| title_full_unstemmed | <i>Candida tropicalis</i> endocarditis: Treatment in a resource-poor setting |
| title_short | <i>Candida tropicalis</i> endocarditis: Treatment in a resource-poor setting |
| title_sort | i candida tropicalis i endocarditis treatment in a resource poor setting |
| topic | Amphotericin B <i>Candida tropicalis</i> fungal endocarditis tricuspid valve |
| url | http://www.annalspc.com/article.asp?issn=0974-2069;year=2010;volume=3;issue=2;spage=174;epage=177;aulast=Kumar |
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