Pesticides in the Blood Samples of Spray-workers at Agriculture Environment: The Toxicological Evaluation
Pesticides are major contaminating chemicals in agriculture environment and a hazard to exposed population. These compounds are absorbed by inhalation, ingestion, and dermal contact. Their bioavailability in the individuals can lead to a variety of metabolic and systemic dysfunctions, and even outri...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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National Centre of Excellence in Analytical Chemsitry
2008-06-01
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| Series: | Pakistan Journal of Analytical & Environmental Chemistry |
| Subjects: | |
| Online Access: | http://www.ceacsu.edu.pk/PDF%20file/Journal%20Vol%209%20No%201/06-PJAEC-300408-07-B.pdf |
| _version_ | 1811297783312809984 |
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| author | A.M. Soomro G.M. Seehar M.I Bhanger N.A. Channa |
| author_facet | A.M. Soomro G.M. Seehar M.I Bhanger N.A. Channa |
| author_sort | A.M. Soomro |
| collection | DOAJ |
| description | Pesticides are major contaminating chemicals in agriculture environment and a hazard to exposed population. These compounds are absorbed by inhalation, ingestion, and dermal contact. Their bioavailability in the individuals can lead to a variety of metabolic and systemic dysfunctions, and even outright disease states. Therefore, the tremendous usage of pesticides has promoted toxicological studies in spraying community. This study comprising pesticide spray-workers (n=140) and controls (n=110) indicated highly significant effects by analytical means on serum cholinesterase level (p<0.001) through ANOVA. Duncan Multiple Range Test ranking for monocrotophos and carbaryl were similar though different than endosulfan and cypermethrin, which conceptualized the effects on cholinesterase level. The GC-MS detection of residue concentrations in blood serum samples of spray-workers; calculated for endosulfan, monocrotophos, carbaryl and cypermethrin were 0.009, 0.005, 0.05 and 0.08 mg/kg body weight respectively. It was further seen in light of reported NOAEL that indicated the effect and extent of exposure among the study population. |
| first_indexed | 2024-04-13T06:10:16Z |
| format | Article |
| id | doaj.art-e82295f713b946a88d2122c919e49174 |
| institution | Directory Open Access Journal |
| issn | 1996-918X 2221-5255 |
| language | English |
| last_indexed | 2024-04-13T06:10:16Z |
| publishDate | 2008-06-01 |
| publisher | National Centre of Excellence in Analytical Chemsitry |
| record_format | Article |
| series | Pakistan Journal of Analytical & Environmental Chemistry |
| spelling | doaj.art-e82295f713b946a88d2122c919e491742022-12-22T02:59:06ZengNational Centre of Excellence in Analytical ChemsitryPakistan Journal of Analytical & Environmental Chemistry1996-918X2221-52552008-06-01913237Pesticides in the Blood Samples of Spray-workers at Agriculture Environment: The Toxicological EvaluationA.M. SoomroG.M. SeeharM.I BhangerN.A. ChannaPesticides are major contaminating chemicals in agriculture environment and a hazard to exposed population. These compounds are absorbed by inhalation, ingestion, and dermal contact. Their bioavailability in the individuals can lead to a variety of metabolic and systemic dysfunctions, and even outright disease states. Therefore, the tremendous usage of pesticides has promoted toxicological studies in spraying community. This study comprising pesticide spray-workers (n=140) and controls (n=110) indicated highly significant effects by analytical means on serum cholinesterase level (p<0.001) through ANOVA. Duncan Multiple Range Test ranking for monocrotophos and carbaryl were similar though different than endosulfan and cypermethrin, which conceptualized the effects on cholinesterase level. The GC-MS detection of residue concentrations in blood serum samples of spray-workers; calculated for endosulfan, monocrotophos, carbaryl and cypermethrin were 0.009, 0.005, 0.05 and 0.08 mg/kg body weight respectively. It was further seen in light of reported NOAEL that indicated the effect and extent of exposure among the study population.http://www.ceacsu.edu.pk/PDF%20file/Journal%20Vol%209%20No%201/06-PJAEC-300408-07-B.pdfPesticidesResiduesAcetylcholinesterase |
| spellingShingle | A.M. Soomro G.M. Seehar M.I Bhanger N.A. Channa Pesticides in the Blood Samples of Spray-workers at Agriculture Environment: The Toxicological Evaluation Pakistan Journal of Analytical & Environmental Chemistry Pesticides Residues Acetylcholinesterase |
| title | Pesticides in the Blood Samples of Spray-workers at Agriculture Environment: The Toxicological Evaluation |
| title_full | Pesticides in the Blood Samples of Spray-workers at Agriculture Environment: The Toxicological Evaluation |
| title_fullStr | Pesticides in the Blood Samples of Spray-workers at Agriculture Environment: The Toxicological Evaluation |
| title_full_unstemmed | Pesticides in the Blood Samples of Spray-workers at Agriculture Environment: The Toxicological Evaluation |
| title_short | Pesticides in the Blood Samples of Spray-workers at Agriculture Environment: The Toxicological Evaluation |
| title_sort | pesticides in the blood samples of spray workers at agriculture environment the toxicological evaluation |
| topic | Pesticides Residues Acetylcholinesterase |
| url | http://www.ceacsu.edu.pk/PDF%20file/Journal%20Vol%209%20No%201/06-PJAEC-300408-07-B.pdf |
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