Biochemical mechanisms of cataract in diabetes mellitus

Cataract is one of the most common diabetes mellitus complication among the adult population worldwide. The purpose of this review is to describe how reactive oxigen species (ROS) are produced, the antioxidant enzymes involved in their neutralization, and the molecular mechanisms associated with hyp...

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Main Authors: Daniela MIRICESCU, Maria GREABU, Constantin STEFANI, Iulia-Ioana STANESCU, Ana Maria Alexandra STANESCU, Alexandra TOTAN
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2020-03-01
Series:Romanian Journal of Medical Practice
Subjects:
Online Access:https://rjmp.com.ro/articles/2020.1/RJMP_2020_1_Art-05.pdf
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author Daniela MIRICESCU
Maria GREABU
Constantin STEFANI
Iulia-Ioana STANESCU
Ana Maria Alexandra STANESCU
Alexandra TOTAN
author_facet Daniela MIRICESCU
Maria GREABU
Constantin STEFANI
Iulia-Ioana STANESCU
Ana Maria Alexandra STANESCU
Alexandra TOTAN
author_sort Daniela MIRICESCU
collection DOAJ
description Cataract is one of the most common diabetes mellitus complication among the adult population worldwide. The purpose of this review is to describe how reactive oxigen species (ROS) are produced, the antioxidant enzymes involved in their neutralization, and the molecular mechanisms associated with hyperglycemia that contributes to cataract development.
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spelling doaj.art-e8270c7eb0ca4feb8924b431cfa4ec2a2022-12-21T18:28:59ZengAmaltea Medical Publishing HouseRomanian Journal of Medical Practice1842-82582069-61082020-03-01151242710.37897/RJMP.2020.1.5Biochemical mechanisms of cataract in diabetes mellitusDaniela MIRICESCU0Maria GREABU1Constantin STEFANI2Iulia-Ioana STANESCU3Ana Maria Alexandra STANESCU4Alexandra TOTAN5Department of Biochemistry, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, RomaniaDepartment of Biochemistry, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, RomaniaDepartment of Family Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; “Carol Davila” University Central Emergency Military Hospital, Bucharest, RomaniaDepartment of Physiology, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, RomaniaDepartment of Family Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, RomaniaDepartment of Biochemistry, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, RomaniaCataract is one of the most common diabetes mellitus complication among the adult population worldwide. The purpose of this review is to describe how reactive oxigen species (ROS) are produced, the antioxidant enzymes involved in their neutralization, and the molecular mechanisms associated with hyperglycemia that contributes to cataract development.https://rjmp.com.ro/articles/2020.1/RJMP_2020_1_Art-05.pdfdiabetes mellituscataractbiochemical mechanisms
spellingShingle Daniela MIRICESCU
Maria GREABU
Constantin STEFANI
Iulia-Ioana STANESCU
Ana Maria Alexandra STANESCU
Alexandra TOTAN
Biochemical mechanisms of cataract in diabetes mellitus
Romanian Journal of Medical Practice
diabetes mellitus
cataract
biochemical mechanisms
title Biochemical mechanisms of cataract in diabetes mellitus
title_full Biochemical mechanisms of cataract in diabetes mellitus
title_fullStr Biochemical mechanisms of cataract in diabetes mellitus
title_full_unstemmed Biochemical mechanisms of cataract in diabetes mellitus
title_short Biochemical mechanisms of cataract in diabetes mellitus
title_sort biochemical mechanisms of cataract in diabetes mellitus
topic diabetes mellitus
cataract
biochemical mechanisms
url https://rjmp.com.ro/articles/2020.1/RJMP_2020_1_Art-05.pdf
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