Splicing inhibition mediated by reduced splicing factors and helicases is associated with the cellular response of lung cancer cells to cisplatin

Splicing inhibition mediated by reduced splicing factors and helicases is associated with the cellular response of lung cancer cells to cisplatin

Lung cancer’s mortality is predominantly linked to post-chemotherapy recurrence, driven by the reactivation of dormant cancer cells. Despite the critical role of these reactivated cells in cancer recurrence and metastasis, the molecular mechanisms governing their therapeutic selection remain poorly...

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Bibliographic Details
Main Authors: Lujuan Wang, Na Yin, Wenhua Shi, Yaohuan Xie, Junqi Yi, Ziying Tang, Jingqun Tang, Juanjuan Xiang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Cell dormancy
Chemotherapy
Lung adenocarcinoma cells
Splicing inhibition
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037023005147

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