Clinical and radiological features and screening of risk factors of reversible posterior encephalopathy syndrome in preeclampsia patients
Objective To analyze clinical and radiological features of preeclampsia combined with reversible posterior encephalopathy syndrome (RPES) and screen related risk factors. Methods Clinical data of 111 preeclampsia patients were recorded, including age, number of pregnancies, systolic blood pressure...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tianjin Huanhu Hospital
2018-05-01
|
| Series: | Chinese Journal of Contemporary Neurology and Neurosurgery |
| Subjects: | |
| Online Access: | http://www.cjcnn.org/index.php/cjcnn/article/view/1779 |
| _version_ | 1819077937259872256 |
|---|---|
| author | Chao-bo BAI Xiao-yu DONG Jian-fei NAO |
| author_facet | Chao-bo BAI Xiao-yu DONG Jian-fei NAO |
| author_sort | Chao-bo BAI |
| collection | DOAJ |
| description | Objective To analyze clinical and radiological features of preeclampsia combined with reversible posterior encephalopathy syndrome (RPES) and screen related risk factors. Methods Clinical data of 111 preeclampsia patients were recorded, including age, number of pregnancies, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), hemoglobin, blood platelet count, serum creatinine (Cr) and plasma D?dimer. Head MRI were examined in all patients. Univariate and multivariate forward Logistic regression analysis were used to screen related risk factors of preeclampsia combined with RPES. Results In 111 patients, 42 were combined with RPES. Logistic regression analysis showed headache (OR = 70.958, 95%CI: 6.578-765.447; P = 0.000), visual disturbance (OR = 3.966, 95%CI: 1.290-12.191; P = 0.016), SBP (OR = 1.034, 95%CI: 1.006-1.064; P = 0.019) and serum Cr (OR = 1.060, 95%CI: 1.000-1.123; P = 0.048) were independent risk factors of preeclampsia combined with RPES. MRI showed the lesions of preeclampsia combined with RPES were located in frontal lobe (17 cases, 40.48% ), temporal lobe (6 cases, 14.29% ), parietal lobe (32 cases, 76.19% ), occipital lobe (35 cases, 83.33%), brain stem (4 cases, 9.52%), cerebellum (7 cases, 16.67%) and basal ganglia (22 cases, 52.38%). MRI showed T1WI hypointensity, T2WI and FLAIR hyperintensity, diffusion ? weighted imaging (DWI) hyperintensity and apparent diffusion coefficient (ADC) hypointensity. Conclusions Headache, visual disturbance, SBP and serum Cr level are independent risk factors of reeclampsia combined with RPES, which are closely related to the onset of RPES.
DOI: 10.3969/j.issn.1672-6731.2018.05.008 |
| first_indexed | 2024-12-21T19:05:08Z |
| format | Article |
| id | doaj.art-e82fa0ce271c4ee487f70fa8957d7b31 |
| institution | Directory Open Access Journal |
| issn | 1672-6731 |
| language | English |
| last_indexed | 2024-12-21T19:05:08Z |
| publishDate | 2018-05-01 |
| publisher | Tianjin Huanhu Hospital |
| record_format | Article |
| series | Chinese Journal of Contemporary Neurology and Neurosurgery |
| spelling | doaj.art-e82fa0ce271c4ee487f70fa8957d7b312022-12-21T18:53:23ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312018-05-0118534234810.3969/j.issn.1672-6731.2018.05.0081734Clinical and radiological features and screening of risk factors of reversible posterior encephalopathy syndrome in preeclampsia patientsChao-bo BAI0Xiao-yu DONG1Jian-fei NAO2Department of Neurology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, ChinaDepartment of Neurology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, ChinaDepartment of Neurology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, ChinaObjective To analyze clinical and radiological features of preeclampsia combined with reversible posterior encephalopathy syndrome (RPES) and screen related risk factors. Methods Clinical data of 111 preeclampsia patients were recorded, including age, number of pregnancies, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), hemoglobin, blood platelet count, serum creatinine (Cr) and plasma D?dimer. Head MRI were examined in all patients. Univariate and multivariate forward Logistic regression analysis were used to screen related risk factors of preeclampsia combined with RPES. Results In 111 patients, 42 were combined with RPES. Logistic regression analysis showed headache (OR = 70.958, 95%CI: 6.578-765.447; P = 0.000), visual disturbance (OR = 3.966, 95%CI: 1.290-12.191; P = 0.016), SBP (OR = 1.034, 95%CI: 1.006-1.064; P = 0.019) and serum Cr (OR = 1.060, 95%CI: 1.000-1.123; P = 0.048) were independent risk factors of preeclampsia combined with RPES. MRI showed the lesions of preeclampsia combined with RPES were located in frontal lobe (17 cases, 40.48% ), temporal lobe (6 cases, 14.29% ), parietal lobe (32 cases, 76.19% ), occipital lobe (35 cases, 83.33%), brain stem (4 cases, 9.52%), cerebellum (7 cases, 16.67%) and basal ganglia (22 cases, 52.38%). MRI showed T1WI hypointensity, T2WI and FLAIR hyperintensity, diffusion ? weighted imaging (DWI) hyperintensity and apparent diffusion coefficient (ADC) hypointensity. Conclusions Headache, visual disturbance, SBP and serum Cr level are independent risk factors of reeclampsia combined with RPES, which are closely related to the onset of RPES. DOI: 10.3969/j.issn.1672-6731.2018.05.008http://www.cjcnn.org/index.php/cjcnn/article/view/1779Pre-eclampsiaPosterior leukoencephalopathy syndromeMagnetic resonance imagingRisk factors |
| spellingShingle | Chao-bo BAI Xiao-yu DONG Jian-fei NAO Clinical and radiological features and screening of risk factors of reversible posterior encephalopathy syndrome in preeclampsia patients Chinese Journal of Contemporary Neurology and Neurosurgery Pre-eclampsia Posterior leukoencephalopathy syndrome Magnetic resonance imaging Risk factors |
| title | Clinical and radiological features and screening of risk factors of reversible posterior encephalopathy syndrome in preeclampsia patients |
| title_full | Clinical and radiological features and screening of risk factors of reversible posterior encephalopathy syndrome in preeclampsia patients |
| title_fullStr | Clinical and radiological features and screening of risk factors of reversible posterior encephalopathy syndrome in preeclampsia patients |
| title_full_unstemmed | Clinical and radiological features and screening of risk factors of reversible posterior encephalopathy syndrome in preeclampsia patients |
| title_short | Clinical and radiological features and screening of risk factors of reversible posterior encephalopathy syndrome in preeclampsia patients |
| title_sort | clinical and radiological features and screening of risk factors of reversible posterior encephalopathy syndrome in preeclampsia patients |
| topic | Pre-eclampsia Posterior leukoencephalopathy syndrome Magnetic resonance imaging Risk factors |
| url | http://www.cjcnn.org/index.php/cjcnn/article/view/1779 |
| work_keys_str_mv | AT chaobobai clinicalandradiologicalfeaturesandscreeningofriskfactorsofreversibleposteriorencephalopathysyndromeinpreeclampsiapatients AT xiaoyudong clinicalandradiologicalfeaturesandscreeningofriskfactorsofreversibleposteriorencephalopathysyndromeinpreeclampsiapatients AT jianfeinao clinicalandradiologicalfeaturesandscreeningofriskfactorsofreversibleposteriorencephalopathysyndromeinpreeclampsiapatients |