MtDNA variations in three main ethnic groups in Tuzla Canton of Bosnia and Herzegovina
This study was based on the analysis of mtDNA polymorphisms in three ethnic groups of Tuzla Canton of Bosnia and Herzegovina (Bosniaks, Croats and Serbs). The main aim of this study was to analyze the influences of the maternal gene flow on the genetic profile of ethnic groups. The analysis of mtDN...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
University of Sarajevo, Institute for Genetic Engineering and Biotechnology
2019-06-01
|
| Series: | Genetics & Applications |
| Online Access: | https://genapp.ba/editions/index.php/journal/article/view/40 |
| _version_ | 1811188178385633280 |
|---|---|
| author | Adisa Ahmić Rifat Hadžiselimović Elma Silajdžić Irma Mujkić Naris Pojskić |
| author_facet | Adisa Ahmić Rifat Hadžiselimović Elma Silajdžić Irma Mujkić Naris Pojskić |
| author_sort | Adisa Ahmić |
| collection | DOAJ |
| description |
This study was based on the analysis of mtDNA polymorphisms in three ethnic groups of Tuzla Canton of Bosnia and Herzegovina (Bosniaks, Croats and Serbs). The main aim of this study was to analyze the influences of the maternal gene flow on the genetic profile of ethnic groups. The analysis of mtDNA variation based on relevant restriction fragment length polymorphisms (RFLP) in combination with HVSI variations of the control region enabled the identification of the Western - Eurasian haplogroups (H, I, J, T, W, U, HV, HVO, K, V, X), African/Near East lineages N1a and Asian haplogroup M. Our data indicate a close gene similarity among maternal gene pools of the ethnic groups of Tuzla Canton as well as similar influence of the maternal gene flow on genetic structure of those populations. The presence of important maternal determinants of the Late Glacial expansion (U5a), postglacial re-colonisation of Europe from refugia of southwestern Europe (H, V, U5b1), central-eastern European Plain (U4), Italian Peninsula (U5b3) and Neolithic expansion (U3, N1a, J, T) was noted in the genetic structure of the ethnic groups in Tuzla Canton. Conclusions in our study are consistent with the results of previous studies based on the distribution of mtDNA haplogroups and Y - chromosome haplogroups in three main ethnic groups of modern Bosnia and Herzegovina, suggesting similar effects of the paternal and maternal gene flows on genetic structure of the three main ethnic groups of modern Bosnia and Herzegovina.
|
| first_indexed | 2024-04-11T14:15:10Z |
| format | Article |
| id | doaj.art-e8345d83630746c5ad454a5d22af3a4c |
| institution | Directory Open Access Journal |
| issn | 2566-2937 2566-431X |
| language | English |
| last_indexed | 2024-04-11T14:15:10Z |
| publishDate | 2019-06-01 |
| publisher | University of Sarajevo, Institute for Genetic Engineering and Biotechnology |
| record_format | Article |
| series | Genetics & Applications |
| spelling | doaj.art-e8345d83630746c5ad454a5d22af3a4c2022-12-22T04:19:33ZengUniversity of Sarajevo, Institute for Genetic Engineering and BiotechnologyGenetics & Applications2566-29372566-431X2019-06-0131MtDNA variations in three main ethnic groups in Tuzla Canton of Bosnia and HerzegovinaAdisa Ahmić0Rifat Hadžiselimović1Elma Silajdžić2Irma Mujkić3Naris Pojskić4University of Tuzla, Faculty of Science Tuzla, Bosnia and HerzegovinaUniversity of Sarajevo - Institute for Genetic Engineering and Biotechnology, Sarajevo, Bosnia and HerzegovinaUniversity of Sarajevo - Institute for Genetic Engineering and Biotechnology, Sarajevo, Bosnia and HerzegovinaUniversity of Tuzla, Faculty of Science Tuzla, Bosnia and HerzegovinaUniversity of Sarajevo – Institute for Genetic Engineering and Biotechnology, Zmaja od Bosne 8, 71 000 Sarajevo, Bosnia and Herzegovina This study was based on the analysis of mtDNA polymorphisms in three ethnic groups of Tuzla Canton of Bosnia and Herzegovina (Bosniaks, Croats and Serbs). The main aim of this study was to analyze the influences of the maternal gene flow on the genetic profile of ethnic groups. The analysis of mtDNA variation based on relevant restriction fragment length polymorphisms (RFLP) in combination with HVSI variations of the control region enabled the identification of the Western - Eurasian haplogroups (H, I, J, T, W, U, HV, HVO, K, V, X), African/Near East lineages N1a and Asian haplogroup M. Our data indicate a close gene similarity among maternal gene pools of the ethnic groups of Tuzla Canton as well as similar influence of the maternal gene flow on genetic structure of those populations. The presence of important maternal determinants of the Late Glacial expansion (U5a), postglacial re-colonisation of Europe from refugia of southwestern Europe (H, V, U5b1), central-eastern European Plain (U4), Italian Peninsula (U5b3) and Neolithic expansion (U3, N1a, J, T) was noted in the genetic structure of the ethnic groups in Tuzla Canton. Conclusions in our study are consistent with the results of previous studies based on the distribution of mtDNA haplogroups and Y - chromosome haplogroups in three main ethnic groups of modern Bosnia and Herzegovina, suggesting similar effects of the paternal and maternal gene flows on genetic structure of the three main ethnic groups of modern Bosnia and Herzegovina. https://genapp.ba/editions/index.php/journal/article/view/40 |
| spellingShingle | Adisa Ahmić Rifat Hadžiselimović Elma Silajdžić Irma Mujkić Naris Pojskić MtDNA variations in three main ethnic groups in Tuzla Canton of Bosnia and Herzegovina Genetics & Applications |
| title | MtDNA variations in three main ethnic groups in Tuzla Canton of Bosnia and Herzegovina |
| title_full | MtDNA variations in three main ethnic groups in Tuzla Canton of Bosnia and Herzegovina |
| title_fullStr | MtDNA variations in three main ethnic groups in Tuzla Canton of Bosnia and Herzegovina |
| title_full_unstemmed | MtDNA variations in three main ethnic groups in Tuzla Canton of Bosnia and Herzegovina |
| title_short | MtDNA variations in three main ethnic groups in Tuzla Canton of Bosnia and Herzegovina |
| title_sort | mtdna variations in three main ethnic groups in tuzla canton of bosnia and herzegovina |
| url | https://genapp.ba/editions/index.php/journal/article/view/40 |
| work_keys_str_mv | AT adisaahmic mtdnavariationsinthreemainethnicgroupsintuzlacantonofbosniaandherzegovina AT rifathadziselimovic mtdnavariationsinthreemainethnicgroupsintuzlacantonofbosniaandherzegovina AT elmasilajdzic mtdnavariationsinthreemainethnicgroupsintuzlacantonofbosniaandherzegovina AT irmamujkic mtdnavariationsinthreemainethnicgroupsintuzlacantonofbosniaandherzegovina AT narispojskic mtdnavariationsinthreemainethnicgroupsintuzlacantonofbosniaandherzegovina |