Effectiveness of an ocular adhesive polyhedral oligomeric silsesquioxane hybrid thermo-responsive FK506 hydrogel in a murine model of dry eye

Effectiveness of an ocular adhesive polyhedral oligomeric silsesquioxane hybrid thermo-responsive FK506 hydrogel in a murine model of dry eye

Dry eye is a common ocular disease that results in discomfort and impaired vision, impacting an individual's quality of life. A great number of drugs administered in eye drops to treat dry eye are poorly soluble in water and are rapidly eliminated from the ocular surface, which limits their the...

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Bibliographic Details
Main Authors:	Yi Han, Lu Jiang, Huihui Shi, Chenfang Xu, Minting Liu, Qingjian Li, Lan Zheng, Hong Chi, Mingyue Wang, Zuguo Liu, Mingliang You, Xian Jun Loh, Yun-Long Wu, Zibiao Li, Cheng Li
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2022-03-01
Series:	Bioactive Materials
Subjects:	Ocular adhesive Polyhedral oligomeric silsesquioxane FK506 Dry eye
Online Access:	http://www.sciencedirect.com/science/article/pii/S2452199X21003595

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