Deciphering the Hypoxia-immune interface in esophageal squamous carcinoma: a prognostic network model

Deciphering the Hypoxia-immune interface in esophageal squamous carcinoma: a prognostic network model

IntroductionThe rapid progress and poor prognosis of the exercise of esophageal squamous cell carcinoma (ESCA) bring great challenges to the treatment. Hypoxia in the tumor microenvironment has become a key factor in the pathogenesis of tumors. However, due to the lack of clear therapeutic targets,...

Full description

Bibliographic Details
Main Authors:	Jie Hu, Qilong Liu, Bi Feng, Yanling Lu, Kai Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-12-01
Series:	Frontiers in Oncology
Subjects:	esophageal squamous cell carcinoma (ESCA) hypoxia weighted gene co-expression network analysis (WGCNA) immune infiltration prognostic biomarkers
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1296814/full

Similar Items

Identification of Immune-Cell-Related Prognostic Biomarkers of Esophageal Squamous Cell Carcinoma Based on Tumor Microenvironment
by: Yiyao Cui, et al.
Published: (2021-10-01)

SKA1/2/3 is a prognostic and predictive biomarker in esophageal adenocarcinoma and squamous cell carcinoma
by: Liming Zhang, et al.
Published: (2024-11-01)

Identification and Validation of a Prognostic Immune-Related Gene Signature in Esophageal Squamous Cell Carcinoma
by: Kai Xiong, et al.
Published: (2022-04-01)

M1A and m7G modification-related genes are potential biomarkers for survival prognosis and for deciphering the tumor immune microenvironment in esophageal squamous cell carcinoma
by: Ruixi Wang, et al.
Published: (2023-06-01)

Heparanase is a prognostic biomarker independent of tumor purity and hypoxia based on bioinformatics and immunohistochemistry analysis of esophageal squamous cell carcinoma
by: Yu Wang, et al.
Published: (2022-07-01)

Identification and validation of prognostic and immunotherapeutic responses in esophageal squamous carcinoma based on hypoxia phenotype-related genes
by: Kai Xie, et al.
Published: (2024-03-01)

Construction of lncRNA prognostic model related to cuproptosis in esophageal carcinoma
by: Liming Zhang, et al.
Published: (2023-04-01)

Establishment of a risk model by integrating hypoxia genes in predicting prognosis of esophageal squamous cell carcinoma
by: Wanyi Xiao, et al.
Published: (2023-01-01)

Prognostic significance of Glasgow prognostic score in patients undergoing esophagectomy for esophageal squamous cell carcinoma
by: Ji-Feng Feng, et al.
Published: (2014-01-01)

Prognostic factors for esophageal respiratory fistula in unresectable esophageal squamous cell carcinoma treated with radiotherapy
by: Jia-Chao Qi, et al.
Published: (2024-07-01)

A prognostic model based on 10 gene signatures associated with intestinal microbiota predicts survival prognosis of esophageal squamous cell adenocarcinoma
by: Jiang Du, et al.
Published: (2022-12-01)

Prognostic Value of SPOCD1 in Esophageal Squamous Cell Carcinoma: A Comprehensive Study Based on Bioinformatics and Validation
by: Zhizhong Lin, et al.
Published: (2022-05-01)

Esophageal Squamous Cell Carcinoma with Marked Eosinophil Infiltration
by: Minoru Fukuchi, et al.
Published: (2011-11-01)

RNA sequencing reveals the expression profiles of circRNA and identifies a four-circRNA signature acts as a prognostic marker in esophageal squamous cell carcinoma
by: Weiwei Wang, et al.
Published: (2021-03-01)

Immunohistochemistry and oxygen saturation endoscopic imaging reveal hypoxia in submucosal invasive esophageal squamous cell carcinoma
by: Nobuhisa Minakata, et al.
Published: (2023-08-01)

The prognostic value of tumor length to resectable esophageal squamous cell carcinoma: a retrospective study
by: Xiangwei Zhang, et al.
Published: (2017-01-01)

Identification and validation of UBE2B as a prognostic biomarker promoting the development of esophageal carcinomas
by: Han Ding, et al.
Published: (2024-02-01)

Identification of POU4F1 as a novel prognostic biomarker and therapeutic target in esophageal squamous cell carcinoma
by: Nan Li, et al.
Published: (2024-08-01)

Identification of prognostic hypoxia-related genes signature on the tumor microenvironment in esophageal cancer
by: Linlin Tan, et al.
Published: (2021-09-01)

A comprehensive genomic characterization of esophageal squamous cell carcinoma: from prognostic analysis to in vivo assay
by: Yuan-Bin Chen, et al.
Published: (2016-08-01)

The efficacy of neoadjuvant immunotherapy and lymphocyte subset predictors in locally advanced esophageal squamous cell carcinoma: A retrospective study
by: Ruotong Wang, et al.
Published: (2024-09-01)

Systematic profiling of ferroptosis gene signatures predicts prognostic factors in esophageal squamous cell carcinoma
by: Tong Lu, et al.
Published: (2021-06-01)

Evaluation of Serum Exosomal lncRNAs as Diagnostic and Prognostic Biomarkers for Esophageal Squamous Cell Carcinoma
by: Yan S, et al.
Published: (2020-10-01)

Phenotypic profiling and prognostic significance of immune infiltrates in esophageal squamous cell carcinoma
by: Chuqing Pan, et al.
Published: (2021-01-01)

A novel hypoxia-associated gene signature for prognosis prediction in head and neck squamous cell carcinoma
by: Jingyi Luo, et al.
Published: (2023-11-01)

Prognostic significance and immune microenvironment infiltration patterns of hypoxia and endoplasmic reticulum stress-related genes in gastric cancer
by: Libin Li, et al.
Published: (2025-02-01)

Prognostic value of esophageal cancer immune prognostic index in advanced esophageal squamous cell carcinoma patients with anti‐programmed cell death‐1 therapy
by: Jiangyue Lu, et al.
Published: (2023-05-01)

Identification of Key Genes Related to the Prognosis of Esophageal Squamous Cell Carcinoma Based on Chip Re-Annotation
by: Meiqi Wang, et al.
Published: (2021-04-01)

NS1-binding protein radiosensitizes esophageal squamous cell carcinoma by transcriptionally suppressing c-Myc
by: Yuwen Wang, et al.
Published: (2018-06-01)

High expression of MARVELD3 as a potential prognostic biomarker for oral squamous cell carcinoma
by: Ke Huang, et al.
Published: (2022-10-01)

Development and validation of a novel prognostic model for patients with surgically resected esophageal squamous cell carcinoma
by: Haiyang Hu, et al.
Published: (2022-08-01)

Immunohistochemical Analysis of P53 and PRB in Esophageal Squamous Cell Carcinoma
by: Biswajit Dey, et al.
Published: (2014-05-01)

Prognostic Nutritional Index as a Prognostic Indicator for the Occurrence of Postoperative Complications in Patients with Esophageal Squamous Cell Carcinoma Following Neoadjuvant Immunochemotherapy
by: Zou W, et al.
Published: (2024-06-01)

A novel disulfidptosis-related LncRNA prognostic risk model: predicts the prognosis, tumor microenvironment and drug sensitivity in esophageal squamous cell carcinoma
by: Chunlin Ye, et al.
Published: (2024-11-01)

METTL3 Is Associated With the Malignancy of Esophageal Squamous Cell Carcinoma and Serves as a Potential Immunotherapy Biomarker
by: Yubin Zhou, et al.
Published: (2022-04-01)

Oxidative stress genes in patients with esophageal squamous cell carcinoma: construction of a novel prognostic signature and characterization of tumor microenvironment infiltration
by: Wei Liu, et al.
Published: (2022-09-01)

miR-4443 promotes radiation resistance of esophageal squamous cell carcinoma via targeting PTPRJ
by: Xiaobo Shi, et al.
Published: (2022-12-01)

Identification and analysis of hub genes of hypoxia-immunity in type 2 diabetes mellitus
by: Jing Li, et al.
Published: (2023-04-01)

A tricarboxylic acid cycle-based machine learning model to select effective drug targets for the treatment of esophageal squamous cell carcinoma
by: Yicheng Liang, et al.
Published: (2023-06-01)

Expression and correlation of Surfeit 4 gene in esophageal squamous cell carcinoma
by: Jun-xing Liu, et al.
Published: (2024-12-01)