Protein Kinase R Restricts the Intracellular Survival of Mycobacterium tuberculosis by Promoting Selective Autophagy

Protein Kinase R Restricts the Intracellular Survival of Mycobacterium tuberculosis by Promoting Selective Autophagy

Tuberculosis (TB) is a deadly infectious lung disease caused by the pathogenic bacterium Mycobacterium tuberculosis (Mtb). The identification of macrophage signaling proteins exploited by Mtb during infection will enable the development of alternative host-directed therapies (HDT) for TB. HDT strate...

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Bibliographic Details
Main Authors:	Robin Smyth, Stefania Berton, Nusrah Rajabalee, Therese Chan, Jim Sun
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-01-01
Series:	Frontiers in Microbiology
Subjects:	Mycobacterium tuberculosis macrophage signaling autophagy host-directed therapy Protein Kinase R
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2020.613963/full

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