Solitary ulcerated plaque on the face - an unusual presentation of cutaneous plasmacytosis?
Abstract Cutaneous and systemic plasmacytosis is a rare disorder characterized by cutaneous polyclonal plasma cell infiltration frequently associated with polyclonal hypergammaglobulinemia and lymphadenopathy. We report a case of a 67-year-old woman with an inflammatory ulcerated plaque in the left...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Dermatologia
2017-06-01
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| Series: | Anais Brasileiros de Dermatologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000300410&tlng=en |
| _version_ | 1819284797134995456 |
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| author | Ana Marta António João Vitor Alves Ricardo Coelho Elvira Bártolo |
| author_facet | Ana Marta António João Vitor Alves Ricardo Coelho Elvira Bártolo |
| author_sort | Ana Marta António |
| collection | DOAJ |
| description | Abstract Cutaneous and systemic plasmacytosis is a rare disorder characterized by cutaneous polyclonal plasma cell infiltration frequently associated with polyclonal hypergammaglobulinemia and lymphadenopathy. We report a case of a 67-year-old woman with an inflammatory ulcerated plaque in the left masseter region. A skin biopsy showed dense perivascular infiltrate of mature plasma cells in the dermis without atypia and immunoglobulin light chain restriction. After physical examination and further investigation, we ruled out systemic disease. Our patient was successfully treated only with hydrocortisone cream application. Few cases of isolated benign primary cutaneous plasmacytosis have been described, particularly in children. After excluding the diagnosis of a reactive process to an infection, which is unlikely in this case, we suspected of a rare manifestation of primary cutaneous plasmacytosis in adults with distinct presentation and clinical course. |
| first_indexed | 2024-12-24T01:53:05Z |
| format | Article |
| id | doaj.art-e83777dfb9724d91afea81d2ef81ecee |
| institution | Directory Open Access Journal |
| issn | 0365-0596 |
| language | English |
| last_indexed | 2024-12-24T01:53:05Z |
| publishDate | 2017-06-01 |
| publisher | Sociedade Brasileira de Dermatologia |
| record_format | Article |
| series | Anais Brasileiros de Dermatologia |
| spelling | doaj.art-e83777dfb9724d91afea81d2ef81ecee2022-12-21T17:21:40ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962017-06-0192341041210.1590/abd1806-4841.20175355Solitary ulcerated plaque on the face - an unusual presentation of cutaneous plasmacytosis?Ana Marta AntónioJoão Vitor AlvesRicardo CoelhoElvira BártoloAbstract Cutaneous and systemic plasmacytosis is a rare disorder characterized by cutaneous polyclonal plasma cell infiltration frequently associated with polyclonal hypergammaglobulinemia and lymphadenopathy. We report a case of a 67-year-old woman with an inflammatory ulcerated plaque in the left masseter region. A skin biopsy showed dense perivascular infiltrate of mature plasma cells in the dermis without atypia and immunoglobulin light chain restriction. After physical examination and further investigation, we ruled out systemic disease. Our patient was successfully treated only with hydrocortisone cream application. Few cases of isolated benign primary cutaneous plasmacytosis have been described, particularly in children. After excluding the diagnosis of a reactive process to an infection, which is unlikely in this case, we suspected of a rare manifestation of primary cutaneous plasmacytosis in adults with distinct presentation and clinical course.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000300410&tlng=enImmunoglobulin light chainsHypergammaglobulinemiaPlasmacytoma |
| spellingShingle | Ana Marta António João Vitor Alves Ricardo Coelho Elvira Bártolo Solitary ulcerated plaque on the face - an unusual presentation of cutaneous plasmacytosis? Anais Brasileiros de Dermatologia Immunoglobulin light chains Hypergammaglobulinemia Plasmacytoma |
| title | Solitary ulcerated plaque on the face - an unusual presentation of cutaneous plasmacytosis? |
| title_full | Solitary ulcerated plaque on the face - an unusual presentation of cutaneous plasmacytosis? |
| title_fullStr | Solitary ulcerated plaque on the face - an unusual presentation of cutaneous plasmacytosis? |
| title_full_unstemmed | Solitary ulcerated plaque on the face - an unusual presentation of cutaneous plasmacytosis? |
| title_short | Solitary ulcerated plaque on the face - an unusual presentation of cutaneous plasmacytosis? |
| title_sort | solitary ulcerated plaque on the face an unusual presentation of cutaneous plasmacytosis |
| topic | Immunoglobulin light chains Hypergammaglobulinemia Plasmacytoma |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000300410&tlng=en |
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