Therapeutic Potential of Hispidin—Fungal and Plant Polyketide

There is a large number of bioactive polyketides well-known for their anticancer, antibiotic, cholesterol-lowering, and other therapeutic functions, and hispidin is among them. It is a highly abundant secondary plant and fungal metabolite, which is investigated in research devoted to cancer, metabol...

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Main Authors: Kseniia A. Palkina, Daria A. Ipatova, Ekaterina S. Shakhova, Anastasia V. Balakireva, Nadezhda M. Markina
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Journal of Fungi
Subjects:
Online Access:https://www.mdpi.com/2309-608X/7/5/323
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author Kseniia A. Palkina
Daria A. Ipatova
Ekaterina S. Shakhova
Anastasia V. Balakireva
Nadezhda M. Markina
author_facet Kseniia A. Palkina
Daria A. Ipatova
Ekaterina S. Shakhova
Anastasia V. Balakireva
Nadezhda M. Markina
author_sort Kseniia A. Palkina
collection DOAJ
description There is a large number of bioactive polyketides well-known for their anticancer, antibiotic, cholesterol-lowering, and other therapeutic functions, and hispidin is among them. It is a highly abundant secondary plant and fungal metabolite, which is investigated in research devoted to cancer, metabolic syndrome, cardiovascular, neurodegenerative, and viral diseases. This review summarizes over 20 years of hispidin studies of its antioxidant, anti-inflammatory, anti-apoptotic, antiviral, and anti-cancer cell activity.
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spelling doaj.art-e8408e19afef4567a8516961f66e65022023-11-21T16:37:06ZengMDPI AGJournal of Fungi2309-608X2021-04-017532310.3390/jof7050323Therapeutic Potential of Hispidin—Fungal and Plant PolyketideKseniia A. Palkina0Daria A. Ipatova1Ekaterina S. Shakhova2Anastasia V. Balakireva3Nadezhda M. Markina4Department of Biomolecular Chemistry, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, RussiaDepartment of Biomolecular Chemistry, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, RussiaDepartment of Biomolecular Chemistry, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, RussiaDepartment of Biomolecular Chemistry, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, RussiaDepartment of Biomolecular Chemistry, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, RussiaThere is a large number of bioactive polyketides well-known for their anticancer, antibiotic, cholesterol-lowering, and other therapeutic functions, and hispidin is among them. It is a highly abundant secondary plant and fungal metabolite, which is investigated in research devoted to cancer, metabolic syndrome, cardiovascular, neurodegenerative, and viral diseases. This review summarizes over 20 years of hispidin studies of its antioxidant, anti-inflammatory, anti-apoptotic, antiviral, and anti-cancer cell activity.https://www.mdpi.com/2309-608X/7/5/323hispidinpolyketidesantioxidanttherapeutic potential
spellingShingle Kseniia A. Palkina
Daria A. Ipatova
Ekaterina S. Shakhova
Anastasia V. Balakireva
Nadezhda M. Markina
Therapeutic Potential of Hispidin—Fungal and Plant Polyketide
Journal of Fungi
hispidin
polyketides
antioxidant
therapeutic potential
title Therapeutic Potential of Hispidin—Fungal and Plant Polyketide
title_full Therapeutic Potential of Hispidin—Fungal and Plant Polyketide
title_fullStr Therapeutic Potential of Hispidin—Fungal and Plant Polyketide
title_full_unstemmed Therapeutic Potential of Hispidin—Fungal and Plant Polyketide
title_short Therapeutic Potential of Hispidin—Fungal and Plant Polyketide
title_sort therapeutic potential of hispidin fungal and plant polyketide
topic hispidin
polyketides
antioxidant
therapeutic potential
url https://www.mdpi.com/2309-608X/7/5/323
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