Non-Absorbable Oral Gentamicin Sulphate: Biopharmaceutical and Dosage Form Evaluation

Non-Absorbable Oral Gentamicin Sulphate: Biopharmaceutical and Dosage Form Evaluation

Gentamicin sulphate is an antibiotic belonging to the aminoglycosides and to class III of the Biopharmaceutical Classification System (BCS). Gentamicin sulphate is highly water soluble, but has very low intestinal permeability. The wide use is because of its broad spectrum of activity. In the curren...

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Bibliographic Details
Main Authors: Nwakile Dozie C., Dozie-Nwakile O.C., Okoye E.I., Umeyor C.E., Uronnachi E.C., Uchendu I.K., Attama A.A., Okore V.C.
Format: Article
Language:English
Published: Sciendo 2021-04-01
Series:European Pharmaceutical Journal
Subjects:
oral dosage form
gentamicin sulphate
enterobacteria
permeation enhancers
mucosal barrier
systemic circulation
Online Access:https://doi.org/10.2478/afpuc-2020-0016

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