Effect of office hysteroscopy on in-vitro fertilization in a fertility centre in Abuja, Nigeria: A prospective study

Background: Fifteen percent of married couples worldwide experience infertility despite unprotected intercourse and approximately 50% of infertile women has uterine pathologies. The success of in vitro fertilization can be assessed using various measures including pregnancy rate, implantation rate...

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Main Authors: Nyoyoko NP, Wada I, Mamiso J
Format: Article
Language:English
Published: Nigerian Medical Association, Akwa Ibom State Branch 2024-01-01
Series:Ibom Medical Journal
Online Access:https://ibommedicaljournal.org/index.php/imjhome/article/view/370
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author Nyoyoko NP
Wada I
Mamiso J
author_facet Nyoyoko NP
Wada I
Mamiso J
author_sort Nyoyoko NP
collection DOAJ
description Background: Fifteen percent of married couples worldwide experience infertility despite unprotected intercourse and approximately 50% of infertile women has uterine pathologies. The success of in vitro fertilization can be assessed using various measures including pregnancy rate, implantation rate and the most acceptable, live birth rate. Various modalities have been employed to investigate endometrial pathologies responsible for infertility. Objectives: To determine and compare the incidence, and pathology in infertile women seen on hysteroscopy and TVS, and the effect on IVF success Methods: This study had 41 participants, 24 had previous Assisted Reproductive Therapy while 17 had not undergone the process. The 41 participants included those that had both TVS and office hysteroscopy. Abnormal findings were recorded and management carried out based on the abnormality detected. Result: Forty-one infertile women aged 26 to 45 years were included in the study. About fifty-eight percent had history of IVF attempts, while 41.46% had no history of IVF. TVS and hysteroscopic examinations were performed on all the patients. TVS findings indicated 26.83% normal findings and 73.17% abnormal pelvic findings. Hysteroscopic findings showed 90.25% patients had abnormal uterine findings Conclusion: This study shows that Hysteroscopy is more sensitive and useful in the diagnosis and treatment of infertility than TVS. Diagnostic measures for hysteroscopic detection of uterine lesions revealed a sensitivity of 78.95% (95% CI 62.68- 90.45), 100% specificity and positive predictive value, with a Negative predictive value of 33.33% (95% CI 21.27 – 48.07) and diagnostic accuracy of 80.95% (95% CI 65.88 – 91.40). These are in keeping with other studies.
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spelling doaj.art-e84713c70bda41898859d6c406753d342024-03-06T11:55:06ZengNigerian Medical Association, Akwa Ibom State BranchIbom Medical Journal1597-71882735-99642024-01-0117110.61386/imj.v17i1.370Effect of office hysteroscopy on in-vitro fertilization in a fertility centre in Abuja, Nigeria: A prospective studyNyoyoko NP0Wada I1Mamiso J2Department of Obstetrics and Gynaecology, University of Uyo Teaching Hospital, Uyo, NigeriaNisa Medical Group, Abuja, NigeriaCare Fertility Bath, England, United Kingdom Background: Fifteen percent of married couples worldwide experience infertility despite unprotected intercourse and approximately 50% of infertile women has uterine pathologies. The success of in vitro fertilization can be assessed using various measures including pregnancy rate, implantation rate and the most acceptable, live birth rate. Various modalities have been employed to investigate endometrial pathologies responsible for infertility. Objectives: To determine and compare the incidence, and pathology in infertile women seen on hysteroscopy and TVS, and the effect on IVF success Methods: This study had 41 participants, 24 had previous Assisted Reproductive Therapy while 17 had not undergone the process. The 41 participants included those that had both TVS and office hysteroscopy. Abnormal findings were recorded and management carried out based on the abnormality detected. Result: Forty-one infertile women aged 26 to 45 years were included in the study. About fifty-eight percent had history of IVF attempts, while 41.46% had no history of IVF. TVS and hysteroscopic examinations were performed on all the patients. TVS findings indicated 26.83% normal findings and 73.17% abnormal pelvic findings. Hysteroscopic findings showed 90.25% patients had abnormal uterine findings Conclusion: This study shows that Hysteroscopy is more sensitive and useful in the diagnosis and treatment of infertility than TVS. Diagnostic measures for hysteroscopic detection of uterine lesions revealed a sensitivity of 78.95% (95% CI 62.68- 90.45), 100% specificity and positive predictive value, with a Negative predictive value of 33.33% (95% CI 21.27 – 48.07) and diagnostic accuracy of 80.95% (95% CI 65.88 – 91.40). These are in keeping with other studies. https://ibommedicaljournal.org/index.php/imjhome/article/view/370
spellingShingle Nyoyoko NP
Wada I
Mamiso J
Effect of office hysteroscopy on in-vitro fertilization in a fertility centre in Abuja, Nigeria: A prospective study
Ibom Medical Journal
title Effect of office hysteroscopy on in-vitro fertilization in a fertility centre in Abuja, Nigeria: A prospective study
title_full Effect of office hysteroscopy on in-vitro fertilization in a fertility centre in Abuja, Nigeria: A prospective study
title_fullStr Effect of office hysteroscopy on in-vitro fertilization in a fertility centre in Abuja, Nigeria: A prospective study
title_full_unstemmed Effect of office hysteroscopy on in-vitro fertilization in a fertility centre in Abuja, Nigeria: A prospective study
title_short Effect of office hysteroscopy on in-vitro fertilization in a fertility centre in Abuja, Nigeria: A prospective study
title_sort effect of office hysteroscopy on in vitro fertilization in a fertility centre in abuja nigeria a prospective study
url https://ibommedicaljournal.org/index.php/imjhome/article/view/370
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AT mamisoj effectofofficehysteroscopyoninvitrofertilizationinafertilitycentreinabujanigeriaaprospectivestudy