Fractional flow reserve in assessment of intermediate non-culprit lesions in acute myocardial infarction
Context: Percutaneous coronary intervention (PCI) of intermediate non-culprit arteries can reduce death or heart attack risk in patients with acute myocardial infarction and multivessel coronary artery disease. Aims: To compare the effectiveness of fractional flow reserve (FFR)-guided PCI with an...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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GarVal Editorial Ltda.
2023-09-01
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| Series: | Journal of Pharmacy & Pharmacognosy Research |
| Subjects: | |
| Online Access: | https://jppres.com/jppres/pdf/vol11/jppres23.1696_11.5.823.pdf |
| _version_ | 1797682566866665472 |
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| author | Do Truong Son Chau Quang Binh Truong Do Anh Nguyen Manh Thong Le Dinh Dat Nguyen Anh Tien Hoang |
| author_facet | Do Truong Son Chau Quang Binh Truong Do Anh Nguyen Manh Thong Le Dinh Dat Nguyen Anh Tien Hoang |
| author_sort | Do Truong Son Chau |
| collection | DOAJ |
| description | Context: Percutaneous coronary intervention (PCI) of intermediate non-culprit arteries can reduce death or heart attack risk in patients with acute myocardial infarction and multivessel coronary artery disease.
Aims: To compare the effectiveness of fractional flow reserve (FFR)-guided PCI with angiography-guided PCI for intermediate non-culprit lesions in patients with acute myocardial infarction and multivessel coronary artery disease.
Methods: In this cohort study, acute myocardial infarction patients with multivessel coronary artery disease who had successful percutaneous coronary intervention of the culprit artery were divided into group of patients receiving FFR-guided PCI (FFR≤0.80, n = 31) and group of patients receiving angiography-guided PCI (diameter stenosis of 50-90%, n = 62) for lesions in non-culprit arteries. These two groups were followed for at least 1 year for major adverse cardiovascular events.
Results: There was no statistically significant difference in major cardiovascular events between FFR-guided percutaneous coronary intervention group and angiography-guided percutaneous coronary intervention group. However, FFR-guided percutaneous coronary intervention group had a lower mortality rate compared to the angiography-guided percutaneous coronary intervention group (3.2% vs. 4.8%). Additionally, there were no reported cases of myocardial infarction in angiography-guided PCI group, while angiography-guided PCI group had a rate of 1.6%.
Conclusions: This study found that it remains uncertain whether FFR-guided PCI is superior than angiography-guided PCI for intermediate non-culprit lesions in patients with acute myocardial infarction and multivessel coronary artery disease. |
| first_indexed | 2024-03-12T00:01:36Z |
| format | Article |
| id | doaj.art-e848fd14427a4803b088fc8520ded1fb |
| institution | Directory Open Access Journal |
| issn | 0719-4250 |
| language | English |
| last_indexed | 2024-03-12T00:01:36Z |
| publishDate | 2023-09-01 |
| publisher | GarVal Editorial Ltda. |
| record_format | Article |
| series | Journal of Pharmacy & Pharmacognosy Research |
| spelling | doaj.art-e848fd14427a4803b088fc8520ded1fb2023-09-17T19:03:25ZengGarVal Editorial Ltda.Journal of Pharmacy & Pharmacognosy Research0719-42502023-09-0111582383210.56499/jppres23.1696_11.5.823Fractional flow reserve in assessment of intermediate non-culprit lesions in acute myocardial infarctionDo Truong Son Chau0Quang Binh Truong1Do Anh Nguyen2Manh Thong Le3Dinh Dat Nguyen4Anh Tien Hoang5Department of Internal Medicine, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam. Department of Interventional Cardiology, Gia Dinh People’s Hospital, Ho Chi Minh, Vietnam.University of Medicine and Pharmacy of Ho Chi Minh City, Ho Chi Minh, Vietnam.Department of Interventional Cardiology, Gia Dinh People’s Hospital, Ho Chi Minh, Vietnam.Department of Interventional Cardiology, Gia Dinh People’s Hospital, Ho Chi Minh, Vietnam.Department of Interventional Cardiology, Gia Dinh People’s Hospital, Ho Chi Minh, Vietnam.Department of Internal Medicine, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam. Department of Medicine, Hue University Hospital, Hue University, Hue, Vietnam.Context: Percutaneous coronary intervention (PCI) of intermediate non-culprit arteries can reduce death or heart attack risk in patients with acute myocardial infarction and multivessel coronary artery disease. Aims: To compare the effectiveness of fractional flow reserve (FFR)-guided PCI with angiography-guided PCI for intermediate non-culprit lesions in patients with acute myocardial infarction and multivessel coronary artery disease. Methods: In this cohort study, acute myocardial infarction patients with multivessel coronary artery disease who had successful percutaneous coronary intervention of the culprit artery were divided into group of patients receiving FFR-guided PCI (FFR≤0.80, n = 31) and group of patients receiving angiography-guided PCI (diameter stenosis of 50-90%, n = 62) for lesions in non-culprit arteries. These two groups were followed for at least 1 year for major adverse cardiovascular events. Results: There was no statistically significant difference in major cardiovascular events between FFR-guided percutaneous coronary intervention group and angiography-guided percutaneous coronary intervention group. However, FFR-guided percutaneous coronary intervention group had a lower mortality rate compared to the angiography-guided percutaneous coronary intervention group (3.2% vs. 4.8%). Additionally, there were no reported cases of myocardial infarction in angiography-guided PCI group, while angiography-guided PCI group had a rate of 1.6%. Conclusions: This study found that it remains uncertain whether FFR-guided PCI is superior than angiography-guided PCI for intermediate non-culprit lesions in patients with acute myocardial infarction and multivessel coronary artery disease.https://jppres.com/jppres/pdf/vol11/jppres23.1696_11.5.823.pdfacute myocardial infarctionfractional flow reserveintermediate non-culprit lesionsmultivessel disease |
| spellingShingle | Do Truong Son Chau Quang Binh Truong Do Anh Nguyen Manh Thong Le Dinh Dat Nguyen Anh Tien Hoang Fractional flow reserve in assessment of intermediate non-culprit lesions in acute myocardial infarction Journal of Pharmacy & Pharmacognosy Research acute myocardial infarction fractional flow reserve intermediate non-culprit lesions multivessel disease |
| title | Fractional flow reserve in assessment of intermediate non-culprit lesions in acute myocardial infarction |
| title_full | Fractional flow reserve in assessment of intermediate non-culprit lesions in acute myocardial infarction |
| title_fullStr | Fractional flow reserve in assessment of intermediate non-culprit lesions in acute myocardial infarction |
| title_full_unstemmed | Fractional flow reserve in assessment of intermediate non-culprit lesions in acute myocardial infarction |
| title_short | Fractional flow reserve in assessment of intermediate non-culprit lesions in acute myocardial infarction |
| title_sort | fractional flow reserve in assessment of intermediate non culprit lesions in acute myocardial infarction |
| topic | acute myocardial infarction fractional flow reserve intermediate non-culprit lesions multivessel disease |
| url | https://jppres.com/jppres/pdf/vol11/jppres23.1696_11.5.823.pdf |
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