Edible Oils Attenuate Button Battery-Induced Injury in Porcine Esophageal Segments
Objective: The objective of the study is to test whether the use of edible oil might be an early treatment strategy for reducing button battery-induced esophageal injury.Methods: A button battery was inserted into esophageal segments collected from pigs. The esophageal segments were randomly allotte...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-03-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fped.2020.00097/full |
| _version_ | 1818851237494259712 |
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| author | Wenyuan Jia Bin Zhang Guanghui Xu Jiangang Xie Haidong Wei Niqi Shan Qianmei Wang Wen Yin Wei Zhao |
| author_facet | Wenyuan Jia Bin Zhang Guanghui Xu Jiangang Xie Haidong Wei Niqi Shan Qianmei Wang Wen Yin Wei Zhao |
| author_sort | Wenyuan Jia |
| collection | DOAJ |
| description | Objective: The objective of the study is to test whether the use of edible oil might be an early treatment strategy for reducing button battery-induced esophageal injury.Methods: A button battery was inserted into esophageal segments collected from pigs. The esophageal segments were randomly allotted to one of the following six treatments: (1) untreated (nothing injected), (2) lemon juice, (3) orange juice, (4) colza oil, (5) peanut oil, and (6) olive oil. Every hour, the battery discharge and the pH value were measured in the esophageal tissue. After treatment for 6 h, the residual voltage of the battery was measured and the esophageal tissue was processed with H&E staining.Results: In esophageal segments of the untreated group, a large area of the mucous membrane was severely eroded. Partial erosion was observed in esophageal tissues treated with either lemon juice or orange juice. Furthermore, the esophageal tissues were basically intact, had little damage when treated with oils. The highest extra-esophageal discharge voltage was recorded in the untreated group, a medium amount of discharge voltage was recorded in the lemon juice and orange juice groups, and the lowest discharge voltage was recorded in all the edible oils groups.Conclusions: Edible oils immersed the battery, reduced the surrounding electrolysis, and thus attenuated battery discharge. As a result, treatment with edible oils attenuated the pH alkalization and tissue damage in button battery injury of pig esophageal segments. These results indicate that edible oils might be used in the treatment of button battery ingestion. |
| first_indexed | 2024-12-19T07:01:50Z |
| format | Article |
| id | doaj.art-e8522da97259424e9a715a0b3e803c4b |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-12-19T07:01:50Z |
| publishDate | 2020-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-e8522da97259424e9a715a0b3e803c4b2022-12-21T20:31:23ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602020-03-01810.3389/fped.2020.00097512087Edible Oils Attenuate Button Battery-Induced Injury in Porcine Esophageal SegmentsWenyuan Jia0Bin Zhang1Guanghui Xu2Jiangang Xie3Haidong Wei4Niqi Shan5Qianmei Wang6Wen Yin7Wei Zhao8Department of Emergency, Xijing Hospital, Air Force Medical University, Xi'an, ChinaDepartment of Emergency, Xijing Hospital, Air Force Medical University, Xi'an, ChinaDivision of Digestive Surgery, Xijing Hospital of Digestive Diseases, Air Force Medical University, Xi'an, ChinaDepartment of Emergency, Xijing Hospital, Air Force Medical University, Xi'an, ChinaDepartment of Anesthesiology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, ChinaDepartment of Emergency, Xijing Hospital, Air Force Medical University, Xi'an, ChinaDepartment of Emergency, Xijing Hospital, Air Force Medical University, Xi'an, ChinaDepartment of Emergency, Xijing Hospital, Air Force Medical University, Xi'an, ChinaDepartment of Emergency, Xijing Hospital, Air Force Medical University, Xi'an, ChinaObjective: The objective of the study is to test whether the use of edible oil might be an early treatment strategy for reducing button battery-induced esophageal injury.Methods: A button battery was inserted into esophageal segments collected from pigs. The esophageal segments were randomly allotted to one of the following six treatments: (1) untreated (nothing injected), (2) lemon juice, (3) orange juice, (4) colza oil, (5) peanut oil, and (6) olive oil. Every hour, the battery discharge and the pH value were measured in the esophageal tissue. After treatment for 6 h, the residual voltage of the battery was measured and the esophageal tissue was processed with H&E staining.Results: In esophageal segments of the untreated group, a large area of the mucous membrane was severely eroded. Partial erosion was observed in esophageal tissues treated with either lemon juice or orange juice. Furthermore, the esophageal tissues were basically intact, had little damage when treated with oils. The highest extra-esophageal discharge voltage was recorded in the untreated group, a medium amount of discharge voltage was recorded in the lemon juice and orange juice groups, and the lowest discharge voltage was recorded in all the edible oils groups.Conclusions: Edible oils immersed the battery, reduced the surrounding electrolysis, and thus attenuated battery discharge. As a result, treatment with edible oils attenuated the pH alkalization and tissue damage in button battery injury of pig esophageal segments. These results indicate that edible oils might be used in the treatment of button battery ingestion.https://www.frontiersin.org/article/10.3389/fped.2020.00097/fullbutton battery ingestionforeign bodyesophageal injuryedible oilsporcine |
| spellingShingle | Wenyuan Jia Bin Zhang Guanghui Xu Jiangang Xie Haidong Wei Niqi Shan Qianmei Wang Wen Yin Wei Zhao Edible Oils Attenuate Button Battery-Induced Injury in Porcine Esophageal Segments Frontiers in Pediatrics button battery ingestion foreign body esophageal injury edible oils porcine |
| title | Edible Oils Attenuate Button Battery-Induced Injury in Porcine Esophageal Segments |
| title_full | Edible Oils Attenuate Button Battery-Induced Injury in Porcine Esophageal Segments |
| title_fullStr | Edible Oils Attenuate Button Battery-Induced Injury in Porcine Esophageal Segments |
| title_full_unstemmed | Edible Oils Attenuate Button Battery-Induced Injury in Porcine Esophageal Segments |
| title_short | Edible Oils Attenuate Button Battery-Induced Injury in Porcine Esophageal Segments |
| title_sort | edible oils attenuate button battery induced injury in porcine esophageal segments |
| topic | button battery ingestion foreign body esophageal injury edible oils porcine |
| url | https://www.frontiersin.org/article/10.3389/fped.2020.00097/full |
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