Recombinant production of a functional SARS-CoV-2 spike receptor binding domain in the green algae Chlamydomonas reinhardtii.

Recombinant production of a functional SARS-CoV-2 spike receptor binding domain in the green algae Chlamydomonas reinhardtii.

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Recombinant production of viral proteins can be used to produce vaccine antigens or reagents to identify antibodies in patient serum. Minimally, these proteins must be correctly folded and have appropriate post-translation modifications. Here we report the production of the SARS-CoV-2 spike protein...

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Bibliographic Details
Main Authors: Anthony J Berndt, Tressa N Smalley, Bijie Ren, Ryan Simkovsky, Amr Badary, Ashley E Sproles, Francis J Fields, Yasin Torres-Tiji, Vanessa Heredia, Stephen P Mayfield
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0257089

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