A novel nonsense mutation of MSH2 gene in a Taiwanese family with hereditary nonpolyposis colorectal cancer

A novel nonsense mutation of MSH2 gene in a Taiwanese family with hereditary nonpolyposis colorectal cancer

Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominant inherited disease predisposing to the development of colorectal cancers and several other malignancies (endometrium, ovaries, stomach, small bowel, hepatobiliary, and urinary tract). HNPCC is caused by germline mutations in a...

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Bibliographic Details
Main Authors: Wen-Chau Chen, Shao-Chieh Lin, Jenq-Chang Lee, 陳文超, 林劭潔, 李政昌
Format: Article
Language:English
Published: Wiley 2011-02-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
HNPCC
Mismatch repair
MSH2 gene
Mutation
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X10000276

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