Sensitization of neonatal rat lumbar motoneuron by the inflammatory pain mediator bradykinin
Bradykinin (Bk) is a potent inflammatory mediator that causes hyperalgesia. The action of Bk on the sensory system is well documented but its effects on motoneurons, the final pathway of the motor system, are unknown. By a combination of patch-clamp recordings and two-photon calcium imaging, we foun...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-03-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/06195 |