Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions
Context: Gastroschisis is a common abdominal wall defect faced by paediatric surgeons worldwide. Early gastroschisis detection, access to improved neonatal intensive care, parenteral nutrition and surgical techniques have led to a reported improvement in mortality of between 4% and 8% in high-income...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | African Journal of Paediatric Surgery |
| Subjects: | |
| Online Access: | http://www.afrjpaedsurg.org/article.asp?issn=0189-6725;year=2023;volume=20;issue=1;spage=46;epage=50;aulast=Machaea |
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| author | Sello S Machaea Milind R Chitnis Phumza Nongena |
| author_facet | Sello S Machaea Milind R Chitnis Phumza Nongena |
| author_sort | Sello S Machaea |
| collection | DOAJ |
| description | Context: Gastroschisis is a common abdominal wall defect faced by paediatric surgeons worldwide. Early gastroschisis detection, access to improved neonatal intensive care, parenteral nutrition and surgical techniques have led to a reported improvement in mortality of between 4% and 8% in high-income countries. In low to middle income countries, such as in Southern Africa, however, there is as much as 84% mortality among patients with gastroschisis. This is thought to be due to factors such as lack of antenatal screening, access to neonatal intensive care services and parenteral nutrition. Aims: The purpose of this study was to calculate the prevalence of gastroschisis and report on its neonatal mortality in the Eastern Cape Province of South Africa. Settings and Design: A retrospective observational study on all neonates with gastroschisis, presenting to a tertiary facility offering paediatric surgical services within the Eastern Cape Province from 1 January 2016 to 31 December 2018. Subjects and Methods: A convenience sampling method was used in retrieving patient files for the study period. Statistical analysis used: Stata version 13. Results: Thirty-seven neonates were included in the study. The prevalence of gastroschisis ranged from 0.07% to 0.18% throughout the 3-year study. The majority (81%) of the neonates were outborn and delivered by mode of caesarean section. Nearly 60% (n = 22) were female. 54% (n = 20) of neonates died within the neonatal period. Conclusions: The majority of the neonates in this study were outborn and female. Although their mortality rate was higher than reported in high-income countries, it was much improved from what is reported in the low to middle income countries. |
| first_indexed | 2024-04-10T09:58:16Z |
| format | Article |
| id | doaj.art-e855361fc2ab4476a45789cf776c36c3 |
| institution | Directory Open Access Journal |
| issn | 0189-6725 |
| language | English |
| last_indexed | 2024-04-10T09:58:16Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | African Journal of Paediatric Surgery |
| spelling | doaj.art-e855361fc2ab4476a45789cf776c36c32023-02-16T12:00:06ZengWolters Kluwer Medknow PublicationsAfrican Journal of Paediatric Surgery0189-67252023-01-01201465010.4103/ajps.ajps_178_21Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutionsSello S MachaeaMilind R ChitnisPhumza NongenaContext: Gastroschisis is a common abdominal wall defect faced by paediatric surgeons worldwide. Early gastroschisis detection, access to improved neonatal intensive care, parenteral nutrition and surgical techniques have led to a reported improvement in mortality of between 4% and 8% in high-income countries. In low to middle income countries, such as in Southern Africa, however, there is as much as 84% mortality among patients with gastroschisis. This is thought to be due to factors such as lack of antenatal screening, access to neonatal intensive care services and parenteral nutrition. Aims: The purpose of this study was to calculate the prevalence of gastroschisis and report on its neonatal mortality in the Eastern Cape Province of South Africa. Settings and Design: A retrospective observational study on all neonates with gastroschisis, presenting to a tertiary facility offering paediatric surgical services within the Eastern Cape Province from 1 January 2016 to 31 December 2018. Subjects and Methods: A convenience sampling method was used in retrieving patient files for the study period. Statistical analysis used: Stata version 13. Results: Thirty-seven neonates were included in the study. The prevalence of gastroschisis ranged from 0.07% to 0.18% throughout the 3-year study. The majority (81%) of the neonates were outborn and delivered by mode of caesarean section. Nearly 60% (n = 22) were female. 54% (n = 20) of neonates died within the neonatal period. Conclusions: The majority of the neonates in this study were outborn and female. Although their mortality rate was higher than reported in high-income countries, it was much improved from what is reported in the low to middle income countries.http://www.afrjpaedsurg.org/article.asp?issn=0189-6725;year=2023;volume=20;issue=1;spage=46;epage=50;aulast=Machaeaabdominal wall defectgastroschisisneonatal mortality |
| spellingShingle | Sello S Machaea Milind R Chitnis Phumza Nongena Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions African Journal of Paediatric Surgery abdominal wall defect gastroschisis neonatal mortality |
| title | Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions |
| title_full | Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions |
| title_fullStr | Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions |
| title_full_unstemmed | Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions |
| title_short | Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions |
| title_sort | prevalence of gastroschisis and its neonatal mortality in the eastern cape province tertiary institutions |
| topic | abdominal wall defect gastroschisis neonatal mortality |
| url | http://www.afrjpaedsurg.org/article.asp?issn=0189-6725;year=2023;volume=20;issue=1;spage=46;epage=50;aulast=Machaea |
| work_keys_str_mv | AT sellosmachaea prevalenceofgastroschisisanditsneonatalmortalityintheeasterncapeprovincetertiaryinstitutions AT milindrchitnis prevalenceofgastroschisisanditsneonatalmortalityintheeasterncapeprovincetertiaryinstitutions AT phumzanongena prevalenceofgastroschisisanditsneonatalmortalityintheeasterncapeprovincetertiaryinstitutions |