Angiogenesis and Melanoma
Angiogenesis occurs in pathological conditions, such as tumors, where a specific critical point in tumor progression is the transition from the avascular to the vascular phase. Tumor angiogenesis depends mainly on the release by neoplastic cells of growth factors specific for endothelial cells, whic...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2010-02-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2072-6694/2/1/114/ |
| _version_ | 1797707358860738560 |
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| author | Vito Longo Tiziana Annese Domenico Ribatti |
| author_facet | Vito Longo Tiziana Annese Domenico Ribatti |
| author_sort | Vito Longo |
| collection | DOAJ |
| description | Angiogenesis occurs in pathological conditions, such as tumors, where a specific critical point in tumor progression is the transition from the avascular to the vascular phase. Tumor angiogenesis depends mainly on the release by neoplastic cells of growth factors specific for endothelial cells, which are able to stimulate the growth of the host’s blood vessels. This article summarizes the literature concerning the relationship between angiogenesis and human melanoma progression. The recent applications of antiangiogenic agents which interfere with melanoma progression are also described. |
| first_indexed | 2024-03-12T06:05:14Z |
| format | Article |
| id | doaj.art-e857778cafc04a21a8be169b069e9801 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-12T06:05:14Z |
| publishDate | 2010-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-e857778cafc04a21a8be169b069e98012023-09-03T03:43:20ZengMDPI AGCancers2072-66942010-02-012111413210.3390/cancers2010114Angiogenesis and MelanomaVito LongoTiziana AnneseDomenico RibattiAngiogenesis occurs in pathological conditions, such as tumors, where a specific critical point in tumor progression is the transition from the avascular to the vascular phase. Tumor angiogenesis depends mainly on the release by neoplastic cells of growth factors specific for endothelial cells, which are able to stimulate the growth of the host’s blood vessels. This article summarizes the literature concerning the relationship between angiogenesis and human melanoma progression. The recent applications of antiangiogenic agents which interfere with melanoma progression are also described.http://www.mdpi.com/2072-6694/2/1/114/angiogenesisantiangiogenesishuman melanomatumor progression |
| spellingShingle | Vito Longo Tiziana Annese Domenico Ribatti Angiogenesis and Melanoma Cancers angiogenesis antiangiogenesis human melanoma tumor progression |
| title | Angiogenesis and Melanoma |
| title_full | Angiogenesis and Melanoma |
| title_fullStr | Angiogenesis and Melanoma |
| title_full_unstemmed | Angiogenesis and Melanoma |
| title_short | Angiogenesis and Melanoma |
| title_sort | angiogenesis and melanoma |
| topic | angiogenesis antiangiogenesis human melanoma tumor progression |
| url | http://www.mdpi.com/2072-6694/2/1/114/ |
| work_keys_str_mv | AT vitolongo angiogenesisandmelanoma AT tizianaannese angiogenesisandmelanoma AT domenicoribatti angiogenesisandmelanoma |