Variant effect predictions capture some aspects of deep mutational scanning experiments

Variant effect predictions capture some aspects of deep mutational scanning experiments

Abstract Background Deep mutational scanning (DMS) studies exploit the mutational landscape of sequence variation by systematically and comprehensively assaying the effect of single amino acid variants (SAVs; also referred to as missense mutations, or non-synonymous Single Nucleotide Variants – miss...

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Bibliografiske detaljer
Main Authors: Jonas Reeb, Theresa Wirth, Burkhard Rost
Format: Article
Sprog:English
Udgivet: BMC 2020-03-01
Serier:BMC Bioinformatics
Fag:
Sequence variation
Variant effect prediction
Deep mutational scanning
Non-synonymous sequence variant
Missense variant
Single nucleotide variant
Online adgang:http://link.springer.com/article/10.1186/s12859-020-3439-4

Internet

http://link.springer.com/article/10.1186/s12859-020-3439-4

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