Variant effect predictions capture some aspects of deep mutational scanning experiments

Variant effect predictions capture some aspects of deep mutational scanning experiments

Abstract Background Deep mutational scanning (DMS) studies exploit the mutational landscape of sequence variation by systematically and comprehensively assaying the effect of single amino acid variants (SAVs; also referred to as missense mutations, or non-synonymous Single Nucleotide Variants – miss...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Jonas Reeb, Theresa Wirth, Burkhard Rost
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: BMC 2020-03-01
Σειρά:BMC Bioinformatics
Θέματα:
Sequence variation
Variant effect prediction
Deep mutational scanning
Non-synonymous sequence variant
Missense variant
Single nucleotide variant
Διαθέσιμο Online:http://link.springer.com/article/10.1186/s12859-020-3439-4

Διαδίκτυο

http://link.springer.com/article/10.1186/s12859-020-3439-4

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