Variant effect predictions capture some aspects of deep mutational scanning experiments

Variant effect predictions capture some aspects of deep mutational scanning experiments

Abstract Background Deep mutational scanning (DMS) studies exploit the mutational landscape of sequence variation by systematically and comprehensively assaying the effect of single amino acid variants (SAVs; also referred to as missense mutations, or non-synonymous Single Nucleotide Variants – miss...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Jonas Reeb, Theresa Wirth, Burkhard Rost
Formatua: Artikulua
Hizkuntza:English
Argitaratua: BMC 2020-03-01
Saila:BMC Bioinformatics
Gaiak:
Sequence variation
Variant effect prediction
Deep mutational scanning
Non-synonymous sequence variant
Missense variant
Single nucleotide variant
Sarrera elektronikoa:http://link.springer.com/article/10.1186/s12859-020-3439-4

Internet

http://link.springer.com/article/10.1186/s12859-020-3439-4

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