Variant effect predictions capture some aspects of deep mutational scanning experiments

Variant effect predictions capture some aspects of deep mutational scanning experiments

Abstract Background Deep mutational scanning (DMS) studies exploit the mutational landscape of sequence variation by systematically and comprehensively assaying the effect of single amino acid variants (SAVs; also referred to as missense mutations, or non-synonymous Single Nucleotide Variants – miss...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Jonas Reeb, Theresa Wirth, Burkhard Rost
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: BMC 2020-03-01
Sarja:BMC Bioinformatics
Aiheet:
Sequence variation
Variant effect prediction
Deep mutational scanning
Non-synonymous sequence variant
Missense variant
Single nucleotide variant
Linkit:http://link.springer.com/article/10.1186/s12859-020-3439-4

Internet

http://link.springer.com/article/10.1186/s12859-020-3439-4

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