Variant effect predictions capture some aspects of deep mutational scanning experiments

Variant effect predictions capture some aspects of deep mutational scanning experiments

Abstract Background Deep mutational scanning (DMS) studies exploit the mutational landscape of sequence variation by systematically and comprehensively assaying the effect of single amino acid variants (SAVs; also referred to as missense mutations, or non-synonymous Single Nucleotide Variants – miss...

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Détails bibliographiques
Auteurs principaux: Jonas Reeb, Theresa Wirth, Burkhard Rost
Format: Article
Langue:English
Publié: BMC 2020-03-01
Collection:BMC Bioinformatics
Sujets:
Sequence variation
Variant effect prediction
Deep mutational scanning
Non-synonymous sequence variant
Missense variant
Single nucleotide variant
Accès en ligne:http://link.springer.com/article/10.1186/s12859-020-3439-4

Internet

http://link.springer.com/article/10.1186/s12859-020-3439-4

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