Variant effect predictions capture some aspects of deep mutational scanning experiments

Variant effect predictions capture some aspects of deep mutational scanning experiments

Abstract Background Deep mutational scanning (DMS) studies exploit the mutational landscape of sequence variation by systematically and comprehensively assaying the effect of single amino acid variants (SAVs; also referred to as missense mutations, or non-synonymous Single Nucleotide Variants – miss...

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Detalhes bibliográficos
Principais autores: Jonas Reeb, Theresa Wirth, Burkhard Rost
Formato: Artigo
Idioma:English
Publicado em: BMC 2020-03-01
coleção:BMC Bioinformatics
Assuntos:
Sequence variation
Variant effect prediction
Deep mutational scanning
Non-synonymous sequence variant
Missense variant
Single nucleotide variant
Acesso em linha:http://link.springer.com/article/10.1186/s12859-020-3439-4

Internet

http://link.springer.com/article/10.1186/s12859-020-3439-4

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