Minor HIV-1 variants with the K103N resistance mutation during intermittent efavirenz-containing antiretroviral therapy and virological failure.

Minor HIV-1 variants with the K103N resistance mutation during intermittent efavirenz-containing antiretroviral therapy and virological failure.

The impact of minor drug-resistant variants of the type 1 immunodeficiency virus (HIV-1) on the failure of antiretroviral therapy remains unclear. We have evaluated the importance of detecting minor populations of viruses resistant to non-nucleoside reverse-transcriptase inhibitors (NNRTI) during in...

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Bibliographic Details
Main Authors: Pierre Delobel, Adrien Saliou, Florence Nicot, Martine Dubois, Stéphanie Trancart, Philippe Tangre, Jean-Pierre Aboulker, Anne-Marie Taburet, Jean-Michel Molina, Patrice Massip, Bruno Marchou, Jacques Izopet, ANRS 106-Window Study Team
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3124548?pdf=render

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