Intrauterine injection of bioengineered hydrogel loaded exosomes derived from HUCM stem cells and spermidine prominently augments the pregnancy rate in thin endometrium rats

Intrauterine injection of bioengineered hydrogel loaded exosomes derived from HUCM stem cells and spermidine prominently augments the pregnancy rate in thin endometrium rats

The endometrium is essential to the development of embryos and pregnancy. Human umbilical cord mesenchymal stem cells (HUCMSCs) are promising stem cell sources. HUCMSCs self-renew quickly and are painless to collect. Spermidine is an inherent polyamine needed for cellular and molecular processes tha...

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Bibliographic Details
Main Authors: Xiuying Lin, Yanqiu Fang, Xuguang Mi, Jianhua Fu, Shiling Chen, Mengxue Wu, Ningyi Jin
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Regenerative Therapy
Subjects:
Hydrogel
Exosomes
Endometrium
Intrauterine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320424000166

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