Cogan’s syndrome: a case report
Cogan's syndrome is a chronic inflammatory disorder of unknown cause affecting mostly young adults. Two main observation of the disease are bilateral interstitial keratitis and vestibuloauditory dysfunction. Association between Cogan's syndrome and systemic vasculitis as well as aortitis a...
| Main Authors: | , , |
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| Format: | Article |
| Language: | fas |
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Golestan University of Medical Sciences
2014-03-01
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| Series: | مجله دانشگاه علوم پزشکی گرگان |
| Subjects: | |
| Online Access: | http://goums.ac.ir/journal/browse.php?a_code=A-10-1-736&slc_lang=en&sid=1 |
| _version_ | 1819124428451086336 |
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| author | Azami A Maleki N Tavosi Z |
| author_facet | Azami A Maleki N Tavosi Z |
| author_sort | Azami A |
| collection | DOAJ |
| description | Cogan's syndrome is a chronic inflammatory disorder of unknown cause affecting mostly young adults. Two main observation of the disease are bilateral interstitial keratitis and vestibuloauditory dysfunction. Association between Cogan's syndrome and systemic vasculitis as well as aortitis are exist. The diagnosis of the disease is based upon the presence of inflammatory eye disease and vestibuloauditory dysfunction . In this article, the classic Cogan's syndrome has been reported in a 47-year-old woman. Two months prior to admission, the patient had been suffering from headache, vertigo, nausea, vomiting, right leg claudication, musculoskeletal pains, bilateral hearing loss and blindness. Ophthalmologic examination revealed that visual acuity was 0.1 bilaterally and on slit lamp examination, there was a conjunctival hyperemia, bilateral cataract and interstitial keratitis. Pure tone audiogram (PTA) and auditory brain stem response (ABR) showed bilateral sensorineural hearing loss. The patient was initially treated with pulse intravenous methylprednisolone and was followed by oral prednisolone and cyclophosphamide, which in follow-up showed partial improvement. |
| first_indexed | 2024-12-22T07:24:05Z |
| format | Article |
| id | doaj.art-e869b3edee1b418893cf6d21912333fe |
| institution | Directory Open Access Journal |
| issn | 1562-4765 2008-4080 |
| language | fas |
| last_indexed | 2024-12-22T07:24:05Z |
| publishDate | 2014-03-01 |
| publisher | Golestan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشگاه علوم پزشکی گرگان |
| spelling | doaj.art-e869b3edee1b418893cf6d21912333fe2022-12-21T18:34:11ZfasGolestan University of Medical Sciencesمجله دانشگاه علوم پزشکی گرگان1562-47652008-40802014-03-01161136140Cogan’s syndrome: a case reportAzami A0Maleki N1Tavosi Z2 Assistant Professor، Department of Internal Medicine, Ardabil University of Medical Sciences, Ardabil, Iran Resident of Internal Medicine, Ardabil University of Medical Sciences, Ardabil, Iran Resident of Internal Medicine, Bushehr University of Medical Sciences, Bushehr, Iran Cogan's syndrome is a chronic inflammatory disorder of unknown cause affecting mostly young adults. Two main observation of the disease are bilateral interstitial keratitis and vestibuloauditory dysfunction. Association between Cogan's syndrome and systemic vasculitis as well as aortitis are exist. The diagnosis of the disease is based upon the presence of inflammatory eye disease and vestibuloauditory dysfunction . In this article, the classic Cogan's syndrome has been reported in a 47-year-old woman. Two months prior to admission, the patient had been suffering from headache, vertigo, nausea, vomiting, right leg claudication, musculoskeletal pains, bilateral hearing loss and blindness. Ophthalmologic examination revealed that visual acuity was 0.1 bilaterally and on slit lamp examination, there was a conjunctival hyperemia, bilateral cataract and interstitial keratitis. Pure tone audiogram (PTA) and auditory brain stem response (ABR) showed bilateral sensorineural hearing loss. The patient was initially treated with pulse intravenous methylprednisolone and was followed by oral prednisolone and cyclophosphamide, which in follow-up showed partial improvement.http://goums.ac.ir/journal/browse.php?a_code=A-10-1-736&slc_lang=en&sid=1Cogan’s syndromeInterstitial keratitisHearing lossVasculitis |
| spellingShingle | Azami A Maleki N Tavosi Z Cogan’s syndrome: a case report مجله دانشگاه علوم پزشکی گرگان Cogan’s syndrome Interstitial keratitis Hearing loss Vasculitis |
| title | Cogan’s syndrome: a case report |
| title_full | Cogan’s syndrome: a case report |
| title_fullStr | Cogan’s syndrome: a case report |
| title_full_unstemmed | Cogan’s syndrome: a case report |
| title_short | Cogan’s syndrome: a case report |
| title_sort | cogan s syndrome a case report |
| topic | Cogan’s syndrome Interstitial keratitis Hearing loss Vasculitis |
| url | http://goums.ac.ir/journal/browse.php?a_code=A-10-1-736&slc_lang=en&sid=1 |
| work_keys_str_mv | AT azamia coganssyndromeacasereport AT malekin coganssyndromeacasereport AT tavosiz coganssyndromeacasereport |